Proceedings of a symposium held in Philadelphia, Pennsylvania, March 18-19, 1994
This conference and monograph were the result of many collective efforts. The whole concept was formulated one early Wednesday morning at our weekly research meeting at Children's Hospital in our division of urology. We have been most fortunate to have a close collaboration with Bob Levin, Ed Macarak, and Pam Howard who have helped steer the course of our division's growing interest in basic science. At our weekly meetings our laboratory fellow will summarize their current work. Other ongoing areas of investigation in our labs and elsewhere are discussed. We have always made an effort to try and understand what other groups are doing who are working in the area of bladder smooth muscle research. It occurred to us that the best way to really know what everyone working in this field was doing would be to sponsor a 2-day meeting where we could all gather to discuss our ongoing work. A major limitation of the annual meeting of the American Urologic Association or the urology section of the American Academy of Pediatrics is that the scientfic sessions are limited as these are meant to be primarily clinical meetings (as they should be). For this reason the idea of a meeting devoted solely to research about the urinary bladder had great appeal. In addition to allowing for longer presentations than the standard 5 to 7 minutes, every effort would be made to encourage a dialogue amongst the presenters and the audience.
The Clinical Relevance of Basic Science: A Surgeon's Perspective; J.W. Duckett Bladder Outlet Obstruction-An Overview; A.J. Wein Bladder Function in Experimental Outlet Obstruction: Pharmacologic Responses to Alterations in Innervation, Energetics, Calcium, Mobilization, and Genetics; R.M. Levin, et al. Electrical Properties of Obstructed Guinea Pig Bladder; J.L. Mostwin, et al. Metabolism of Detrusor Smooth Muscle in Normal and Obstructed Urinary Bladder; B. Uvelius, A. Arner The Neuronal Response to Bladder Outlet Obstruction, a Role for NGF; M.C. DuPont, et al. Contractile Proteins and Their Response to Bladder Outlet Obstruction; S. Chacko, P.A. Longhurst Molecular Aspects of Bladder Outlet Obstruction V.K. Lin, J.D. McConnell Fetal Lower Urinary Tract Physiology: In vivo Studies; R. Mevorach, B. Kogan Developmental Aspects of Excitation Contraction Coupling in Urinary Bladder Smooth Muscle; S.A. Zderic Congenital Bladder Obstruction: Research Strategies and Directions; C.A. Peters Is Collagen Remodeling Associated with Bladder Obstruction? H.P. Ehrlich Regulation of Matrix Metalloproteinases during Extracelluar Matrix Turnover; M.L. Corcoran, et al. Elastic Fibers and Their Role in Bladder Extracelluar Matrix J. Rosenbloom, et al. 20 additional articles. Index.