During the past decade there has been an increasing awareness of the need for a different approach to the problem of bilharziasis. We do know that 180-200 million people are infected and that the infection is increasing but we have not as yet been able to answer the question: Are they suffering from a disease. Study of vital statistics or hospital records, mass biochemical or immunological tests and community surveys have not yet provided the full answer. Gradually and perhaps begrudgingly, we have come to realize that we must study the man initially by means of well controlled clinical observations to obtain evidence for the altered physiology, if any, due to bilharzial infection; secondly and equally imp~rtant through pathological studies on individual patients to determine the structural changes, if any, as a result of infection with this parasite; and by post mortem studies. Experimental studies of bilharzial infection in animals, valuable as they may be for the elucidation of the pathogenesis of the lesions in the laboratory animal and in man cannot serve as a substitute for the precise information on the nature of the possible lesions induced by bilharziasis in man. Basically, the significance of any clinical observation can be evaluated only through reliable pathological confirmation.
The Aim of the Symposium.- The Schistosome Life-Cycle.- The Epidemiology of Bilharziasis.- Clinicopathological Aspects of Hepatosplenic Bilharziasis.- Cardio-Pulmonary Bilharziasis.- Pathological Aspects of Bilharziasis in Egypt.- Some Clinicopathological Aspects of Urinary Bilharziasis.- Malignant Bladder Tumors Associated with Schistosomiasis. A Gross and Microscopic Study.- The Role of Bilharziasis in the Pathogenesis of Bladder Cancer.- Clinical Patterns in Urinary Schistosomiasis.- Egg-Output in Bilharziasis in Relation to Epidemiology, Pathology, Treatment and Control.- Some Remarks on the Clinical and Pathological Aspects of Schistosomiasis in Central Africa.- The Clinico-Pathological Manifestations of Intestinal Bilharziasis in Durban, South Africa.- Schistosomiasis in Ibadan, Western Nigeria.- Bilharziasis in French Speaking West Africa.- The Pathology of Schistosomiasis in Japan. Historical Review of Research in Japan and its Relation to Liver Cirrhosis.- Clinical and Pathological Aspects of Schistosomiasis in Brazil.- Studies on Schistosomiasis Mansoni. Correlation between Clinical Finding, Liver Pathology and Portal Circulation Hemodynamics.- Schistosomiasis Mansoni: Lesions Produced by Dead Worms in Liver and Lung.- The Pathogenesis of Schistosomiasis Mansoni.- Radiological Pathology and Methods of Investigation in Schistosomiasis.- Geographic Pathology of Schistosomiasis Mansoni. Studies on Liver Injury.- Histopathology of Schistosomiasis.- Ecology and the Pathology of Bilharzia.- Experimental Bilharzia.- Immunodiagnosis in Schistosomiasis.- Fluorescent Antibody Studies on the Immunopathology of Schistosomiasis Mansoni.- Mechanisms of Schistosome Immunity.- The Measurement of Schistosome Populations.- A Comparison of Techniques for the Recovery of Schistosome Eggs in Autopsy Material.- Summary and Conclusions. The Need for Research in Bilharziasis.
During the past decade there has been an increasing awareness of the need for a different approach to the problem of bilharziasis. We do know that 180-200 million people are infected and that the infection is increasing but we have not as yet been able to answer the question: Are they suffering from a disease. Study of vital statistics or hospital records, mass biochemical or immunological tests and community surveys have not yet provided the full answer. Gradually and perhaps begrudgingly, we have come to realize that we must study the man initially by means of well controlled clinical observations to obtain evidence for the altered physiology, if any, due to bilharzial infection; secondly and equally imp~rtant through pathological studies on individual patients to determine the structural changes, if any, as a result of infection with this parasite; and by post mortem studies. Experimental studies of bilharzial infection in animals, valuable as they may be for the elucidation of the pathogenesis of the lesions in the laboratory animal and in man cannot serve as a substitute for the precise information on the nature of the possible lesions induced by bilharziasis in man. Basically, the significance of any clinical observation can be evaluated only through reliable pathological confirmation.
Inhaltsverzeichnis
The Aim of the Symposium.- The Schistosome Life-Cycle.- The Epidemiology of Bilharziasis.- Clinicopathological Aspects of Hepatosplenic Bilharziasis.- Cardio-Pulmonary Bilharziasis.- Pathological Aspects of Bilharziasis in Egypt.- Some Clinicopathological Aspects of Urinary Bilharziasis.- Malignant Bladder Tumors Associated with Schistosomiasis. A Gross and Microscopic Study.- The Role of Bilharziasis in the Pathogenesis of Bladder Cancer.- Clinical Patterns in Urinary Schistosomiasis.- Egg-Output in Bilharziasis in Relation to Epidemiology, Pathology, Treatment and Control.- Some Remarks on the Clinical and Pathological Aspects of Schistosomiasis in Central Africa.- The Clinico-Pathological Manifestations of Intestinal Bilharziasis in Durban, South Africa.- Schistosomiasis in Ibadan, Western Nigeria.- Bilharziasis in French Speaking West Africa.- The Pathology of Schistosomiasis in Japan. Historical Review of Research in Japan and its Relation to Liver Cirrhosis.- Clinical and Pathological Aspects of Schistosomiasis in Brazil.- Studies on Schistosomiasis Mansoni. Correlation between Clinical Finding, Liver Pathology and Portal Circulation Hemodynamics.- Schistosomiasis Mansoni: Lesions Produced by Dead Worms in Liver and Lung.- The Pathogenesis of Schistosomiasis Mansoni.- Radiological Pathology and Methods of Investigation in Schistosomiasis.- Geographic Pathology of Schistosomiasis Mansoni. Studies on Liver Injury.- Histopathology of Schistosomiasis.- Ecology and the Pathology of Bilharzia.- Experimental Bilharzia.- Immunodiagnosis in Schistosomiasis.- Fluorescent Antibody Studies on the Immunopathology of Schistosomiasis Mansoni.- Mechanisms of Schistosome Immunity.- The Measurement of Schistosome Populations.- A Comparison of Techniques for the Recovery of Schistosome Eggs in Autopsy Material.- Summary and Conclusions. The Need for Research in Bilharziasis.
Klappentext
During the past decade there has been an increasing awareness of the need for a different approach to the problem of bilharziasis. We do know that 180-200 million people are infected and that the infection is increasing but we have not as yet been able to answer the question: Are they suffering from a disease. Study of vital statistics or hospital records, mass biochemical or immunological tests and community surveys have not yet provided the full answer. Gradually and perhaps begrudgingly, we have come to realize that we must study the man initially by means of well controlled clinical observations to obtain evidence for the altered physiology, if any, due to bilharzial infection; secondly and equally imp~rtant through pathological studies on individual patients to determine the structural changes, if any, as a result of infection with this parasite; and by post mortem studies. Experimental studies of bilharzial infection in animals, valuable as they may be for the elucidation of the pathogenesis of the lesions in the laboratory animal and in man cannot serve as a substitute for the precise information on the nature of the possible lesions induced by bilharziasis in man. Basically, the significance of any clinical observation can be evaluated only through reliable pathological confirmation.
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