Strong evidence for effects of EDCs, including low-level exposures, on humans and wildlife
Comprehensive coverage of mechanisms by which EDCs perturb endocrine systems in exposed organisms as well as in their offspring
Advice to physicians on how to talk to their patients about EDCs in soy formula and other types of exposures
This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.
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Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians´ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.
ContentsPrefaceContributorsPart I. The Basic Biology of Endocrine Disruption1. Introduction to Endocrine-disrupting ChemicalsAndrea C. Gore2. Endocrine Disruption and the FemaleAna M. Soto, Beverly S. Rubin, and Carlos Sonnenschein3. Endocrine Disruption in the MalePrue A. Cowin, Paul M.D. Foster, and Gail P. Risbridger4. Endocrine Disruption and the BrainDeena M. Walker and Andrea C. Gore5. Heavy Metals as Endocrine-disrupting ChemicalsCheryl A. Dyer6. Cellular Mechanisms of Endocrine Disruption: Traditional and NovelActionsStuart R. Adler7. Endocrine Disruptors, Epigenetically Induced Changes, andTransgenerational Transmission of Characters and Epigenetic StatesCarlos Guerrero-Bosagna and Luis ValladaresPart II. The Biology of EDCs in Humans8. Implications of Thyroid Hormone Signaling through thePhosphoinositide-3 Kinase for Xenobiotic Disruption of Human HealthDavid L. Armstrong9. Endocrine Disruption and Reproductive Outcomes in WomenSarah Janssen, Victor Y. Fujimoto, and Linda C. Giudice10. Epidemiologic Evidence on the Relationship between EnvironmentalEndocrine Disruptors and Male Reproductive and Developmental HealthRuss Hauser, Julia S. Barthold, and John D. Meeker11. Human Exposures and Body Burdens of Endocrine-disrupting ChemicalsAntonia M. Calafat and Larry L. NeedhamPart III. Implications and Mitigations of EDCs12. Policy Implications of Endocrine-disrupting Chemicals in HumansTracey J. Woodruff13. Talking with Patients and the Public about Endocrine-DisruptingChemicalsGina Solomon and Sarah Janssen14. Community Interventions to Reduce Exposures to Chemicals withEndocrine Disrupting PropertiesBarbara Brenner and Maida Galvez15. What can we do about Endocrine-Disrupting Chemicals?Joseph Thornton
From the reviews:
"...an excellent introductory overview of endocrine disrupting chemicals. It should be of particular interest to researchers and healthcare professionals in the areas of reproductive biology and thyroid action, and endocrinologists in general." -Doody's Book Review, Weighted Numerical Score: 95 - 4 Stars
"Part of the Series Contemporary Endocrinology, this volume presents the basics, facts and policies relating to environmental chemicals endangering the endocrine system. ... Of interest to environmentalists and endocrinologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)
"This edited book `Endocrine Disrupting Chemicals´ is timely. ... The book is divided into three distinct sections ... . the amount of material covered provides a useful reference for both newcomers to the area, and the more seasoned researcher. This edited volume could serve as a text for a graduate-level course on the subject as the material in many of the chapters would serve to provide the basis for more in-depth discussions of a variety of issues." (Ralph L. Cooper, Endocrine, Vol. 32, 2007)
"This monograph belongs to well known Contemporary Endocrinology Series edited by Humana Press. ... contains more than 1600 valuable references brought up to 2006. It appears useful not only for all MDs of all professions, since it brings fundamental aspects on the topic of EDCs which is touching not only health care professional, but also the general public. Careful presentation of all chapters shows also excellent editorial work which considerably helps to the reader to percept and understand individual problems discussed by the authors." (Endocrine Regulations, February, 2008)
"The book provides a firm and complete review of the current work on EDCs from basic biology to practical guides for clinicians and other professionals. ... It is useful for the basic researcher ... . Overall the book is a unique mix of basic science and practical chapters/guidebooks that focuses on chemicals that can be very harmful and cause dramatic changes in basic development and physiology. ... I recommend it highly as an insightful and timely work on an important issue." (Howard C. Cromwell, General and Comparative Endocrinology, Vol. 160, 2009)
Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians' office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.
The Basic Biology of Endocrine Disruption.- to Endocrine-Disrupting Chemicals.- Endocrine Disruption and the Female.- Endocrine Disruption in the Male.- Endocrine-Disrupting Chemicals and the Brain.- Heavy Metals as Endocrine-Disrupting Chemicals.- Cellular Mechanisms of Endocrine Disruption.- Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States.- The Biology of EDCs in Humans.- Implications of Thyroid Hormone Signaling Through the Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health.- Endocrine Disruption and Reproductive Outcomes in Women.- Epidemiologic Evidence on the Relationship Between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health.- Human Exposures and Body Burdens of Endocrine-Disrupting Chemicals.- Implications and Mitigations of EDCs.- Policy Implications of Endocrine-Disrupting Chemicals in Humans.- Talking With Patients and the Public About Endocrine-Disrupting Chemicals.- Community Interventions to Reduce Exposure to Chemicals with Endocrine-Disrupting Properties.- What Can We Do About Endocrine-Disrupting Chemicals?.
From the reviews:
"...an excellent introductory overview of endocrine disrupting chemicals. It should be of particular interest to researchers and healthcare professionals in the areas of reproductive biology and thyroid action, and endocrinologists in general." -Doody's Book Review, Weighted Numerical Score: 95 - 4 Stars
"Part of the Series Contemporary Endocrinology, this volume presents the basics, facts and policies relating to environmental chemicals endangering the endocrine system. ... Of interest to environmentalists and endocrinologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)
"This edited book 'Endocrine Disrupting Chemicals' is timely. ... The book is divided into three distinct sections ... . the amount of material covered provides a useful reference for both newcomers to the area, and the more seasoned researcher. This edited volume could serve as a text for a graduate-level course on the subject as the material in many of the chapters would serve to provide the basis for more in-depth discussions of a variety of issues." (Ralph L. Cooper, Endocrine, Vol. 32, 2007)
"This monograph belongs to well known Contemporary Endocrinology Series edited by Humana Press. ... contains more than 1600 valuable references brought up to 2006. It appears useful not only for all MDs of all professions, since it brings fundamental aspects on the topic of EDCs which is touching not only health care professional, but also the general public. Careful presentation of all chapters shows also excellent editorial work which considerably helps to the reader to percept and understand individual problems discussed by the authors." (Endocrine Regulations, February, 2008)
"The book provides a firm and complete review of the current work on EDCs from basic biology to practical guides for clinicians and other professionals. ... It is useful for the basic researcher ... . Overall the book is a unique mix ofbasic science and practical chapters/guidebooks that focuses on chemicals that can be very harmful and cause dramatic changes in basic development and physiology. ... I recommend it highly as an insightful and timely work on an important issue." (Howard C. Cromwell, General and Comparative Endocrinology, Vol. 160, 2009)
Inhaltsverzeichnis
Contents
Preface
Contributors
Part I. The Basic Biology of Endocrine Disruption
1. Introduction to Endocrine-disrupting Chemicals
Andrea C. Gore
2. Endocrine Disruption and the Female
Ana M. Soto, Beverly S. Rubin, and Carlos Sonnenschein
3. Endocrine Disruption in the Male
Prue A. Cowin, Paul M.D. Foster, and Gail P. Risbridger
4. Endocrine Disruption and the Brain
Deena M. Walker and Andrea C. Gore
5. Heavy Metals as Endocrine-disrupting Chemicals
Cheryl A. Dyer
6. Cellular Mechanisms of Endocrine Disruption: Traditional and Novel
Actions
Stuart R. Adler
7. Endocrine Disruptors, Epigenetically Induced Changes, and
Transgenerational Transmission of Characters and Epigenetic States
Carlos Guerrero-Bosagna and Luis Valladares
Part II. The Biology of EDCs in Humans
8. Implications of Thyroid Hormone Signaling through the
Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health
David L. Armstrong
9. Endocrine Disruption and Reproductive Outcomes in Women
Sarah Janssen, Victor Y. Fujimoto, and Linda C. Giudice
10. Epidemiologic Evidence on the Relationship between Environmental
Endocrine Disruptors and Male Reproductive and Developmental Health
Russ Hauser, Julia S. Barthold, and John D. Meeker
11. Human Exposures and Body Burdens of Endocrine-disrupting Chemicals
Antonia M. Calafat and Larry L. Needham
Part III. Implications and Mitigations of EDCs
12. Policy Implications of Endocrine-disrupting Chemicals in Humans
Tracey J. Woodruff
13. Talking with Patients and the Public about Endocrine-Disrupting
Chemicals
Gina Solomon and Sarah Janssen
14. Community Interventions to Reduce Exposures to Chemicals with
Endocrine Disrupting Properties
Barbara Brenner and Maida Galvez
15. What can we do about Endocrine-Disrupting Chemicals?
Joseph Thornton
Klappentext
This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.
Strong evidence for effects of EDCs, including low-level exposures, on humans and wildlifenComprehensive coverage of mechanisms by which EDCs perturb endocrine systems in exposed organisms as well as in their offspringnAdvice to physicians on how to talk to their patients about EDCs in soy formula and other types of exposures
