Featuring chapters from the leading authorities responsible for the most significant current scientific and clinical research on neurotoxins
Valuable reference text providing up to date information
Contains information useful to researchers and clinicians in neuroscience and neurology, biochemistry, microbiology and cell biology
Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation with a focus on clinical application. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins and is both up to date and authoritative.
Chapter 1: Overview and History of Botulinum Neurotoxin Research and Exploitation
Chapter 2: Pharmacology of Botulinum Neurotoxins
Chapter 3: Absorption and Transport of Botulinum Neurotoxins
Chapter 4: The Botulinum Neurotoxin Complex and the Role of Ancillary Proteins
Chapter 5: Neurotoxin Structure
Chapter 6: The Dual Receptor Recognition of Botulinum Neurotoxins
Chapter 7: Transloation, entry into the cell
Chapter 8: Protease Activity of the Botulinum Neurotoxins
Chapter 9: Molecular Basis for Persistence of Botulinum Neurotoxin
Chapter 10: Clostridium botulinum Genomes and Genetic Diversity
Chapter 11: Botulinum Neurotoxin Risks and Detection in Environment, Agriculture and Food Chains
Chapter 12: Botulism as a Disease of Humans
Chapter 13: Prevention and Treatment of Botulism
Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins, and is both up to date and authoritative.
Overview and history of botulinum neurotoxin research and exploitation.- Pharmacology of botulinum neurotoxins.- Absorption and transport of botulinum neurotoxins.- The botulinum neurotoxin complex and the role of ancillary proteins.- Neurotoxin structure.- The dual receptor recognition of botulinum neurotoxins.- Translocation, entry into the cell.- Protease activity of the botulinum neurotoxins.- Molecular basis for persistence of botulinum neurotoxins.- Clostridium botulinum genomes and genetic diversity.- Botulinum neurotoxin risks and detection in environment, agriculture and food chains.- Botulism as a disease of humans.- Prevention and treatment of botulism.
Inhaltsverzeichnis
Chapter 1: Overview and History of Botulinum Neurotoxin Research and ExploitationChapter 2: Pharmacology of Botulinum NeurotoxinsChapter 3: Absorption and Transport of Botulinum NeurotoxinsChapter 4: The Botulinum Neurotoxin Complex and the Role of Ancillary ProteinsChapter 5: Neurotoxin StructureChapter 6: The Dual Receptor Recognition of Botulinum NeurotoxinsChapter 7: Transloation, entry into the cellChapter 8: Protease Activity of the Botulinum NeurotoxinsChapter 9: Molecular Basis for Persistence of Botulinum NeurotoxinChapter 10: Clostridium botulinum Genomes and Genetic DiversityChapter 11: Botulinum Neurotoxin Risks and Detection in Environment, Agriculture and Food ChainsChapter 12: Botulism as a Disease of HumansChapter 13: Prevention and Treatment of Botulism
Klappentext
Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation with a focus on clinical application. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins and is both up to date and authoritative.
Featuring chapters from the leading authorities responsible for the most significant current scientific and clinical research on neurotoxins
Valuable reference text providing up to date information
Contains information useful to researchers and clinicians in neuroscience and neurology, biochemistry, microbiology and cell biology
Includes supplementary material: sn.pub/extras
