Interdisciplinary, easy-to-use color atlas and textbook
Approximately 75 cases reflecting the wide spectrum of pathology encountered in the sellar and parasellar region
High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of each lesion subtype
Key operative and clinical management pearls
Gabriel Zada, MD, MS
Department of Neurological Surgery
Keck School of Medicine
University of Southern California
1975 Zonal Avenue
Los Angeles, CA 90033, USA
gzada@usc.edu
M. Beatriz S. Lopes, MD, PhD
Department of Pathology (Neuropathology)
University of Virginia School of Medicine
1215 Lee Street, Room 3060–HEP
Charlottesville, VA 22908, USA
msl2e@virginia.edu
Srinivasan Mukundan, Jr, PhD, MD
Department of Radiology
Brigham and Women´s Hospital
75 Francis Street
Boston, MA 02115 USA
smukundan@partners.org
Edward Laws, Jr, MD
Department of Neurosurgery
Brigham and Women´s Hospital
Harvard Medical School
15 Francis Street
Boston, MA 02115, USA
elaws@partners.org
This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case deillegalscription commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain.
Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.
Section I: Basic Principles
1 Anatomy of the Sellar and Parasellar Region
Luigi Maria Cavallo, Domenico Solari, Alessandro Villa, Teresa Somma, Paolo Cappabianca
2 Imaging of the Sellar Region
Raymond Y. Huang, Srinivasan Mukundan Jr
3 Pituitary Physiology and Endocrinology
Miriam Padilla, John Carmichael
4 Pathology and Molecular Biology of the Pituitary Region
M. Beatriz S. Lopes
5 The Direct Endoscopic Endonasal Transsphenoidal Approach to the Pituitary Gland
Gabriel Zada, Joshua Lucas, Edward Laws
6 Transcranial and Skull Base Surgical Approaches to the Sellar and Parasellar Region
Ian F. Dunn, Arthur L. Day
7 Radiosurgery of the Sellar and Parasellar Region
Robert M. Starke, Ching-Jen Chen, Dale Ding, Jason Sheehan
Section II: The Normal Pituitary Gland
8 The Normal Pituitary Gland
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section III: Pituitary Hyperplasia
9 Pituitary Hyperplasia
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section IV: Pituitary Adenomas
10 Nonfunctioning Pituitary Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
11 Prolactinomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
12 Somatotroph (GH) Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
13 Corticotroph (ACTH) Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
14 Silent Corticotroph (ACTH) Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
15 Thyrotroph (TSH) Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
16 Gonadotroph Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
17 Pituitary Apoplexy
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
18 Atypical Pituitary Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
19 Pituitary Carcinoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
20 Ectopic Pituitary Adenomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section V: Craniopharyngiomas and Other Epithelial Cystic Lesions of the Sellar Region
21 Craniopharyngioma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
22 Rathke Cleft Cyst
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
23 Xanthogranuloma of the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
24 Petrous Apex Cholesterol Granuloma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
25 Sellar Region Arachnoid Cyst
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
26 Sellar Region Epidermoid and Dermoid Cysts
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
27 Colloid Cyst of the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section VI: Other Neoplasms of the Anterior Skull Base, Sellar, and Parasellar Regions
28 Meningioma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
29 Hemangiopericytoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
30 Schwannomas of the Sellar and Parasellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
31 Chordoma and Chondrosarcoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
32 Hemangioblastoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
33 Cavernous Sinus Cavernous Hemangioma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
34 Optic Pathway (Opticochiasmatic) and Hypothalamic Gliomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
35 Pituicytomas and Sellar Ependymomas
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
36 Granular Cell Tumor
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
37 Germ Cell Tumor
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
38 Olfactory Neuroblastoma and Sellar Neuroblastoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
39 Hypothalamic Hamartoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
40 Plasmacytoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
41 Lymphoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
42 Gangliocytoma and Ganglioglioma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
43 Spindle Cell Oncocytoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
44 Nasopharyngeal Carcinoma and Squamous Cell Carcinoma of the Paranasal Sinuses
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
45 Sinonasal Melanoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
46 Sinonasal Adenocarcinoma
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
47 Sinonasal Undifferentiated Carcinoma (SNUC)
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
48 Fibrosarcoma of the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
49 Juvenile Nasopharyngeal Angiofibroma (JNA)
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
50 Metastatic Tumors to the Pituitary Gland
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section VII: Inflammatory and Infectious Lesions of the Anterior Skull Base, Sellar and Parasellar Region
51 Spontaneous Abscess of the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
52 Invasive Fungal Sinusitis and Fungal Abscess of the Sella
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
53 Mucocele and Mucopyocele
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
54 Sellar Tuberculosis
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
55 Neurocysticercosis of the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
56 Granulomatous Conditions
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
57 Inflammatory Hypophysitis
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
58 Demyelinating Diseases: Multiple Sclerosis and Neuromyelitis Optica
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section VIII: Vascular Disorders of the Anterior Skull Base, Sellar, and Parasellar Region
59 Cerebral Aneurysms with Intrasellar Extension
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
60 Arteriovenous Malformations
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
61 Cavernous Malformations (Angiomas) of the Sellar and Suprasellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
62 Vascular Fistulas of the Sellar and Parasellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
63 Carotid Artery Dolichoectasia and Kissing Internal Carotid Arteries
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
64 Sheehan´s Pituitary Infarction
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
65 Persistent Trigeminal Artery of the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section IX: Congenital and Developmental Anomalies of the Anterior Skull Base and Sellar Region
66 Meningoceles and Encephaloceles
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
67 Empty Sella Syndrome
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
68 Pituitary Hypoplasia and Other Midline Developmental Anomalies
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
69 Duplication of the Pituitary Gland
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
70 Fibrous Dysplasia
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
71 Basilar Impression and Invagination
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
Section X: Acquired Anomalies of the Sellar Region
72 Traumatic Injury, Pituitary Stalk Disruption, and Posttraumatic Anosmia
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
73 Spontaneous, Traumatic, and Postoperative CSF Rhinorrhea
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
74 Pseudoaneurysms of the Internal Carotid Artery in the Sellar Region
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
75 Iatrogenic Pituitary Abscess
Gabriel Zada, M. Beatriz S. Lopes, Srinivasan Mukundan Jr, Edward Laws
This book presents, in a stepwise and interactive fashion, approximately 75 clinical-pathological entities that reflect the wide spectrum of pathology encountered in the sellar and parasellar region and have been gathered over a period of decades by the authors. Multiple examples of high-quality radiologic and histopathologic images depicting the differentiating features of the varying lesions are presented, and key operative and clinical management pearls are briefly reviewed in a concise, bullet point format. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary,making this atlas a useful resource for any practitioner or trainee who cares for patients with pituitary disease and anterior skull base pathology. The format is unique in that no similar interdisciplinary book is dedicated specifically to the comprehensive catalogue of lesions in this intricate region of the brain and skull base.
Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.
Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.
This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case deillegalscription commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain.
Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.
Anatomy of the Sellar and Parasellar Region.- Imaging of the Sellar Region.- Pituitary Physiology and Endocrinology.- Pathology and Molecular Biology of the Pituitary Region.- The Direct Endoscopic Endonasal Transsphenoidal Approach to the Pituitary Gland.- Transcranial and Skull Base Surgical Approaches to the Sellar and Parasellar Region.- Radiosurgery of the Sellar and Parasellar Region.- The Normal Pituitary Gland.- Pituitary Hyperplasia.- Nonfunctioning Pituitary Adenomas.- Prolactinomas.- Somatotroph (GH) Adenomas.- Corticotroph (ACTH) Adenomas.- Silent Corticotroph (ACTH) Adenomas.- Thyrotroph (TSH) Adenomas.- Gonadotroph Adenomas.- Pituitary Apoplexy.- Atypical Pituitary Adenomas.- Pituitary Carcinoma.- Ectopic Pituitary Adenomas.- Craniopharyngioma.- Rathke Cleft Cyst.- Xanthogranuloma of the Sellar Region.- Petrous Apex Cholesterol Granuloma.- Sellar Region Arachnoid Cyst.- Sellar Region Epidermoid and Dermoid Cysts.- Colloid Cyst of the Sellar Region.- Meningioma.- Hemangiopericytoma.- Schwannomas of the Sellar and Parasellar Region.- Chordoma and Chondrosarcoma.- Hemangioblastoma.- Cavernous Sinus Cavernous Hemangioma.- Optic Pathway (Opticochiasmatic) and Hypothalamic Gliomas.- Pituicytomas and Sellar Ependymomas.- Granular Cell Tumor.- Germ Cell Tumor.- Olfactory Neuroblastoma and Sellar Neuroblastoma.- Hypothalamic Hamartoma.- Plasmacytoma.- Lymphoma.- Gangliocytoma and Ganglioglioma.- Spindle Cell Oncocytoma.- Nasopharyngeal Carcinoma and Squamous Cell Carcinoma of the Paranasal Sinuses.- Sinonasal Melanoma.- Sinonasal Adenocarcinoma.- Sinonasal Undifferentiated Carcinoma (SNUC).- Fibrosarcoma of the Sellar Region.- Juvenile Nasopharyngeal Angiofibroma (JNA).- Metastatic Tumors to the Pituitary Gland.- Spontaneous Abscess of the Sellar Region.- Invasive Fungal Sinusitis and Fungal Abscess of the Sella.- Mucocele and Mucopyocele.- Sellar Tuberculosis.- Neurocysticercosis of the Sellar Region.- Granulomatous Conditions.- InflammatoryHypophysitis.- Demyelinating Diseases: Multiple Sclerosis and Neuromyelitis Optica.- Cerebral Aneurysms with Intrasellar Extension.- Arteriovenous Malformations.- Cavernous Malformations (Angiomas) of the Sellar and Suprasellar Region.- Vascular Fistulas of the Sellar and Parasellar Region.- Carotid Artery Dolichoectasia and Kissing Internal Carotid Arteries.- Sheehan's Pituitary Infarction.- Persistent Trigeminal Artery of the Sellar Region.- Meningoceles and Encephaloceles.- Empty Sella Syndrome.- Pituitary Hypoplasia and Other Midline Developmental Anomalies.- Duplication of the Pituitary Gland.- Fibrous Dysplasia.- Basilar Impression and Invagination.- Traumatic Injury, Pituitary Stalk Disruption, and Posttraumatic Anosmia.- Spontaneous, Traumatic, and Postoperative CSF Rhinorrhea.- Pseudoaneurysms of the Internal Carotid Artery in the Sellar Region.- Iatrogenic Pituitary Abscess.
Über den Autor
Inhaltsverzeichnis
Anatomy of the Sellar and Parasellar Region.- Imaging of the Sellar Region.- Pituitary Physiology and Endocrinology.- Pathology and Molecular Biology of the Pituitary Region.- The Direct Endoscopic Endonasal Transsphenoidal Approach to the Pituitary Gland.- Transcranial and Skull Base Surgical Approaches to the Sellar and Parasellar Region.- Radiosurgery of the Sellar and Parasellar Region.- The Normal Pituitary Gland.- Pituitary Hyperplasia.- Nonfunctioning Pituitary Adenomas.- Prolactinomas.- Somatotroph (GH) Adenomas.- Corticotroph (ACTH) Adenomas.- Silent Corticotroph (ACTH) Adenomas.- Thyrotroph (TSH) Adenomas.- Gonadotroph Adenomas.- Pituitary Apoplexy.- Atypical Pituitary Adenomas.- Pituitary Carcinoma.- Ectopic Pituitary Adenomas.- Craniopharyngioma.- Rathke Cleft Cyst.- Xanthogranuloma of the Sellar Region.- Petrous Apex Cholesterol Granuloma.- Sellar Region Arachnoid Cyst.- Sellar Region Epidermoid and Dermoid Cysts.- Colloid Cyst of the Sellar Region.- Meningioma.- Hemangiopericytoma.- Schwannomas of the Sellar and Parasellar Region.- Chordoma and Chondrosarcoma.- Hemangioblastoma.- Cavernous Sinus Cavernous Hemangioma.- Optic Pathway (Opticochiasmatic) and Hypothalamic Gliomas.- Pituicytomas and Sellar Ependymomas.- Granular Cell Tumor.- Germ Cell Tumor.- Olfactory Neuroblastoma and Sellar Neuroblastoma.- Hypothalamic Hamartoma.- Plasmacytoma.- Lymphoma.- Gangliocytoma and Ganglioglioma.- Spindle Cell Oncocytoma.- Nasopharyngeal Carcinoma and Squamous Cell Carcinoma of the Paranasal Sinuses.- Sinonasal Melanoma.- Sinonasal Adenocarcinoma.- Sinonasal Undifferentiated Carcinoma (SNUC).- Fibrosarcoma of the Sellar Region.- Juvenile Nasopharyngeal Angiofibroma (JNA).- Metastatic Tumors to the Pituitary Gland.- Spontaneous Abscess of the Sellar Region.- Invasive Fungal Sinusitis and Fungal Abscess of the Sella.- Mucocele and Mucopyocele.- Sellar Tuberculosis.- Neurocysticercosis of the Sellar Region.- Granulomatous Conditions.- InflammatoryHypophysitis.- Demyelinating Diseases: Multiple Sclerosis and Neuromyelitis Optica.- Cerebral Aneurysms with Intrasellar Extension.- Arteriovenous Malformations.- Cavernous Malformations (Angiomas) of the Sellar and Suprasellar Region.- Vascular Fistulas of the Sellar and Parasellar Region.- Carotid Artery Dolichoectasia and Kissing Internal Carotid Arteries.- Sheehan's Pituitary Infarction.- Persistent Trigeminal Artery of the Sellar Region.- Meningoceles and Encephaloceles.- Empty Sella Syndrome.- Pituitary Hypoplasia and Other Midline Developmental Anomalies.- Duplication of the Pituitary Gland.- Fibrous Dysplasia.- Basilar Impression and Invagination.- Traumatic Injury, Pituitary Stalk Disruption, and Posttraumatic Anosmia.- Spontaneous, Traumatic, and Postoperative CSF Rhinorrhea.- Pseudoaneurysms of the Internal Carotid Artery in the Sellar Region.- Iatrogenic Pituitary Abscess
.
Klappentext
This book presents, in a stepwise and interactive fashion, approximately 75 cases that reflect the wide spectrum of pathology encountered in this region. Each case deillegalscription commences with a concise clinical scenario. High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of the lesion subtype in question are then presented, and key operative and clinical management pearls are briefly reviewed. The interdisciplinary nature of this easy-to-use color atlas and textbook reflects the fact that the management of patients with sellar and parasellar lesions is itself often interdisciplinary. The format is unique in that no similar interdisciplinary book is available on lesions of this region of the brain.
Atlas of Sellar and Parasellar Lesions: Clinical, Imaging, and Pathologic Correlations is of great value for practitioners and trainees in a range of medical specialties, including radiology, neurology, endocriniology, pathology, oncology, radiation oncology, and neurosurgery.
Interdisciplinary, easy-to-use color atlas and textbook
rn
Approximately 75 cases reflecting the wide spectrum of pathology encountered in the sellar and parasellar region
rn
High-quality radiologic, laboratory, and histopathologic images depicting the differentiating features of each lesion subtype
rn
Key operative and clinical management pearls
rn
