Section I. Kinases and Phosphatasesn n Significance of Protein Kinase A in Cancern Maria V. Nesterova and Y. S. Cho-Chungn n Protein Kinase C and Cancern Mary E. Reylandn n The Role of PI3K-Akt Signal Transduction in Virus Infectionn Samantha Coorayn n Cyclin-Dependent Kinase 5: A Target for Neuroprotection?n Frank Gillardonn n Critical Roles of the Raf/MEK/ERK Pathway in Apoptosis and Drug Resistancen James A. McCubrey, Fred E. Bertrand, Linda S. Steelman, Fumin Chang, David M. Terrian, and Richard A. Franklinn n MAP Kinases Signaling in Human Diseasesn Philippe Roux and J.Blenisn n Serine/Threonine Protein Phosphates in Apoptosisn Gro Gausdal, Camilla Krakstad, Lars Herfindal, and Stein Ove Doskelandn n Urokinase/Urokinase Receptor-Mediated Signaling in Cancern Sreerama Shetty, and Steven Idelln n Section II. Molecular Basis of Cell Deathn n Signaling Pathways That Protect the Heart Against Apoptosis Induced by Ischemia and Reperfusionn Zheqing Cai and Gregg L. Semenzan n Cyclooxygenase-2 Gene Expression: Transcriptional and Posttranscriptional Controls in Intestinal Tumorigenesisn Shrikant Anant and Sripathi M. Surebann n Death Receptors: Mechanisms, Biology and Therapeutic Potentialn Sharmila Shankar and Rakesh Srivastavan n DNA Damage-Dependent Apoptosisn Tomasz Skorskin n The Role of Proteasome in Apoptosis n Peter Lown n Apoptosis Induction in T Lymphocytes by HIVn Maria Saveria Gilardini Montanin n Inhibitors of Apoptosis Proteins and Caspasesn Jai Yu, John Silke and Paul G. Ekertn n Intracellular Pathways Involved in DNA-Damage and Repair to Neuronal Apoptosisn Maurizio Memon n The Biology of Caspasesn Tasman James Daish and Sharad Kumar
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 and 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer. These comprehensive volumes integrate the most innovative and current findings. The contributors are at the forefront of scientific discovery.
Particular attention is given to apoptosis in human diseases
All of the contributors are at the forefront of scientific discovery