1. Histopathology and Molecular Biology of Prostate Atrophy: A Lesion Associated with Inflammation, PIN, and Prostate Cancer 2. Epigenetic Gene Silencing in Prostate Cancer 3. Inherited Genetic Changes in Prostate Cancer 4. Prostate Molecular Oncogenesis: Gene Deletions and Somatic Mutations 5. Somatic Genetic Changes in Prostate Cancer: Androgen Receptor Alterations 6. Androgen Receptor in Prostate Cancer Progression 7. Epigenetic Modification and Acetylation of Androgen Receptor Regulate Prostate Cellular Growth 8. Estrogen Receptor Alpha and Beta in the Regulation of Normal and Malignant Prostate Epithelium 9. Estrogen Action in Normal Prostate Epithelium and in Prostate Cancer 10. Hypoxia Inducible Factor 1 and Angiogenesis in Prostate Cancer 11. Signal Transduction by the Ras - MAP Kinase Pathway in Prostate Cancer Progression 12. Transcription Factors Stat5 and Stat3: Survival Factors for Prostate Cancer Cells 13. Role of PI3K-Akt and PTEN in the Growth and Progression of Prostate Cancer 14. New Perspectives in Prediction of Clinical Outcome of Prostate Cancer: TMPRSS2-ETS Gene Fusion in Prostate Cancer 15. New Directions in Radiation Therapy of Prostate Cancer: Brachytherapy and Intensity Modulated Radiation Therapy 16. Advances in Surgical Intervention of Prostate Cancer: Comparison of the Benefits and Pitfalls of Retropubic, Perineal and Laparoscopic Radical Prostatectomy 17. Targeted Therapy Trials for Prostate Cancer 18. New Perspectives on Chemotherapy of Prostate Cancer 19. Concluding Remarks: The Future of Prostate Cancer
Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. The authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer and into future, novel treatment strategies.
In this book, award-winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. They focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art book provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. In addition, it discusses clinical trials that have not been covered or evaluated in any other currently available book. Invaluable to physicians and researchers, Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies provides a comprehensive translational resource as well as an important source of information for prostate cancer patients.