Section I. Malignant Transformation and Metastasisn n BCR-ABL and Cancern María Pérez-Caro and Isidro Sanchez-Garcian n Angiogenesis and Cancern Yohei Maeshiman n Metastasis: The Evasion of Apoptosisn Christine E. Horak, Jolie L. Bronder, Amina Bouadis, and Patricia S. Steegn n Carcinogenesis: Balance Between Apoptosis and Survival Pathwaysn Dean G. Tang and Jim Kehrern n Aberrations of DNA Damage Checkpoints in Cancern Marikki Laihon n c-Myc, Apoptosis and Disordered Tissue Growthn Michael Khan and Stella Pelengarisn n Role of Lysophospholipids in Cell Growth and Survivaln Ianjun Fang and Sarah Spiegeln n Alternative Use of Signaling by the GBP Cytokine in Cell Growth and Cancer Control: From Surveillance to Therapyn Livio Mallucci and Valerie Wellsn n Control Nodes Linking the Regulatory Networks of the Cell Cycle and Apoptosisn Baltazar D. Aguda, Wee Kheng Yio, and Felicia Ngn n Section II. Molecular Basis of Disease Therapyn n Regulation of NF B Function: Target for Drug Developmentn Daniel Sliva and Rakesh Srivastavan n 5-Fluorouracil: Molecular Mechanisms of Cell Deathn D. B. Longley and P. G. Johnstonn n Apoptosis-Inducing Cellular Vehicles for Cancer Gene Therapy: Endothelial and Neural Progenitors n Gergely Jarmy, Jiwu Wei, Klaus-Michael Debatin, and Christian Beltingern n Apoptosis and Cancer Therapyn Maurice Reimann, and Clemens Schmittn n Coupling Apoptosis and Cell Division Control in Cancer: The Survivin Paradigmn Dario C. Altierin n Clinical Significance of Histone Deacetylase Inhibitors in Cancern Sharmila Shankar and Rakesh K. Srivastava
These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases.
These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology.
Contributors are at the forefront of scientific discovery
The reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise