Meticulous exploration into state-of-the-art methods and protocols for microarray technology
Authors examine bioinformatics, an important aspect in analyzing large amounts of data that emerge during experiments
Microarray Technology, Volumes 1 and 2, present information in designing and fabricating arrays and binding studies with biological analytes while providing the reader with a broad deillegalscription of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments.
Among the topics discussed in Volume 1: Synthesis Methods, are matrices in the synthesis of microarrays, array optimization processes, array-based comparative genomic hybridization, 60-mer oligonucleotide probes, bifunctional reagents NTMTA and NTPAC, and high density arrays using digital microarray synthesis platforms. Other topics include multiplex ligation-dependent probe amplification (MLPA), hybridization conditions in situ-synthesized oligo arrays, peptide arrays, high density replication tools (HDRT), protocols for the quantification of oligo hybridization, glyco-bead arrays, and an investigation into the emerging nano technology.
Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.
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Microarray Technology, Volumes 1 and 2, comprises a meticulous exploration into state-of-the-art methods and protocols for microarray technology. The volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad deillegalscription of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.
Table of Contents Microarray Technology Volume 1 - Synthesis Methods 1. Introduction: Array Technology - An Overview Hartmut Seliger 2. Current Microarray Surface Chemistries David W. Grainger, Charles H. Greef, Ping Gong and Michael J. Lochhead 3. Non-Fouling Surfaces: A Review of Principles and Applications for Microarray Capture Assay Designs Ping Gong and David W. Grainger 4. Optimization of Oligonucleotide DNA Microarray Martin Dufva and Claus BV Christensen. 5. Detection of DNA Copy Number Alterations in Complex Genomes Using Array CGH Wei-Wen Cai 6. Evaluating the Quality of Data Microarray Measurements Lili Wang, A.K. Gaigalas, M.B. Satterfield, M. Salit, Y. Zong, and J. Noble 7. Construction of Oligonucleotide Microarrays (Biochip) Using Heterobifunctional Reagents Jyoti Choithani, B. Vaijayanthi, Pradeep Kumar, and Kailash Chand Gupta. 8. Choice of Polymer Matrix, its Functionalization and Estimation of Functional Group Density for Preparation of Biochips Shweta Mahajan, B. Vaijayanthi , Gopal Rembhotkar, Kailash Chand Gupta, Pradeep Kumar. 9. Methods in High-Resolution, Array-Based Comparative Genomic Hybridization Mark R. McCormick, Rebecca R. Selzer and Todd A. Richmond 10. Design and Fabrication of Spotted Long Oligonucleotide Microarrays for Gene Expression Cheng-Chung and Konan Peck 11. In-Situ Oligonucleotide Arrays on Plastic Jang B. Rampal , Peter J. Coassin and Robert S. Matson 12. Detecting Ligated Fragments on Oligonucleotide Microarrays - Optimizing Chip Design, Array MLPA Modification and Hybridization Parameters Ian R Berry, Carol A. Delaney, Graham R. Taylor 13. Detection of SNPs in Cancer Related Genes by Minisequencing on a Microelectronic DNA Chip Alexandre Ho-Pun-Cheung, Hafid Abaibou, Philippe Cleuziat and Evelyn Lopez- Crapez 14. Hybridization Analysis Using Oligonucleotide Probe Arrays Robert S. Matson and Jang B. Rampal 15. In situ Synthesis of Peptide Microarrays Using Ink-Jet Microdispensing Bogdan V. Antohe and Patrick W. Cooley 16. Intein-Mediated Peptide Arrays for Epitope Mapping and Kinase/Phosphatase Assays Ming-Qun Xu, Inca Ghosh, Samvel Kochinyan and Luo Sun 17. Printing Low Density Protein Arrays in Microplates Robert S. Matson Raymond C. Milton, Michael C. Cress and Jang B. Rampal 18. Protein Microarray Applications - Forward and Reverse Protein Arrays Yaping Zong, Shanshan Zhang, Huang-Tsu Chen, Yunfei Zong, and Yaxian Shi. 19. Cell Microarray for Functional Exploration of Genomes David Castel, Marie-Anne Debily, Amandine Pitaval and Xavier Gidrol 20. Quantification of Mixed-phase Hybridization on Polymer Microparticles by Europium (III) Ion Fluorescence Kaisa Ketomaki and Harri Lonnberg. 21. Measurement of the Sugar-Binding Specificity of Lectins Using Multiplexed Bead-Based Suspension Arrays Kazuo Yamamoto, Fumiko Yasukawa, and Seiichiro Ito 22. Nanotechnology: Moving from Microarrays Toward Nanoarrays Hua Chen and Jun Li.
These two volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad deillegalscription of microarray technology tools and their potential applications.
Current Microarray Surface Chemistries.- Nonfouling Surfaces.- Optimization of Oligonucleotide DNA Microarrays.- Detection of DNA Copy Number Alterations in Complex Genomes Using Array Comparative Genomic Hybridization.- Evaluating the Quality of Data From Microarray Measurements.- Construction of Oligonucleotide Microarrays (Biochip) Using Heterobifunctional Reagents.- Choice of Polymer Matrix, Its Functionalization and Estimation of Functional Group Density for Preparation of Biochips.- Methods in High-Resolution, Array-Based Comparative Genomic Hybridization.- Design and Fabrication of Spotted Long Oligonucleotide Microarrays for Gene Expression Analysis.- Construction of In Situ Oligonucleotide Arrays on Plastic.- Detecting Ligated Fragments on Oligonucleotide Microarrays.- Detection of Single-Nucleotide Polymorphisms in Cancer-Related Genes by Minisequencing on a Microelectronic DNA Chip.- Hybridization Analysis Using Oligonucleotide Probe Arrays.- In Situ Synthesis of Peptide Microarrays Using Ink-Jet Microdispensing.- Intein-Mediated Peptide Arrays for Epitope Mapping and Kinase/Phosphatase Assays.- Printing Low Density Protein Arrays in Microplates.- Forward-Phase and Reverse-Phase Protein Microarray.- Cell Microarray for Functional Exploration of Genomes.- Quantification of Mixed-Phase Hybridization on Polymer Microparticles by Europium (III) Ion Fluorescence.- Measurement of the Sugar-Binding Specificity of Lectins Using Multiplexed Bead-Based Suspension Arrays.- Nanotechnology.
Microarray Technology, Volumes 1 and 2, comprises a meticulous exploration into state-of-the-art methods and protocols for microarray technology. The volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad deillegalscription of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.
Inhaltsverzeichnis
Table of Contentsn Microarray Technologyn Volume 1 - Synthesis Methods n n 1. Introduction: Array Technology - An Overview n Hartmut Seligern n 2. Current Microarray Surface Chemistriesn David W. Grainger, Charles H. Greef, Ping Gong and Michael J. Lochheadn n 3. Non-Fouling Surfaces: A Review of Principles and Applications for Microarray Capture Assay Designsn Ping Gong and David W. Graingern n 4. Optimization of Oligonucleotide DNA Microarrayn Martin Dufva and Claus BV Christensen. n n 5. Detection of DNA Copy Number Alterations in Complex Genomes Using Array CGH n Wei-Wen Cain n 6. Evaluating the Quality of Data Microarray Measurements n Lili Wang, A.K. Gaigalas, M.B. Satterfield, M. Salit, Y. Zong, and J. Noblen n 7. Construction of Oligonucleotide Microarrays (Biochip) Using Heterobifunctional Reagentsn Jyoti Choithani, B. Vaijayanthi, Pradeep Kumar, and Kailash Chand Gupta.n n 8. Choice of Polymer Matrix, its Functionalization and Estimation of Functional Group Density for Preparation of Biochips n Shweta Mahajan, B. Vaijayanthi , Gopal Rembhotkar, Kailash Chand Gupta, Pradeep Kumar. n n 9. Methods in High-Resolution, Array-Based Comparative Genomic Hybridizationn Mark R. McCormick, Rebecca R. Selzer and Todd A. Richmond n n 10. Design and Fabrication of Spotted Long Oligonucleotide Microarrays for Gene Expression n Cheng-Chung and Konan Peckn n 11. In-Situ Oligonucleotide Arrays on Plastic n Jang B. Rampal , Peter J. Coassin and Robert S. Matsonn n 12. Detecting Ligated Fragments on Oligonucleotide Microarrays - Optimizing Chip Design, Array MLPA Modification and Hybridization Parametersn Ian R Berry, Carol A. Delaney, Graham R. Taylor n n 13. Detection of SNPs in Cancer Related Genes by Minisequencing on a Microelectronic DNA Chip n Alexandre Ho-Pun-Cheung, Hafid Abaibou, Philippe Cleuziat and Evelyn Lopez- Crapez n n 14. Hybridization Analysis Using Oligonucleotide Probe Arrays n Robert S. Matson and Jang B. Rampaln n 15. In situ Synthesis of Peptide Microarrays Using Ink-Jet Microdispensing n Bogdan V. Antohe and Patrick W. Cooleyn n 16. Intein-Mediated Peptide Arrays for Epitope Mapping and Kinase/Phosphatase Assays n Ming-Qun Xu, Inca Ghosh, Samvel Kochinyan and Luo Sunn n 17. Printing Low Density Protein Arrays in Microplates n Robert S. Matson Raymond C. Milton, Michael C. Cress and Jang B. Rampal n n 18. Protein Microarray Applications - Forward and Reverse Protein Arrays n Yaping Zong, Shanshan Zhang, Huang-Tsu Chen, Yunfei Zong, and Yaxian Shi.n n 19. Cell Microarray for Functional Exploration of Genomesn David Castel, Marie-Anne Debily, Amandine Pitaval and Xavier Gidrol n n 20. Quantification of Mixed-phase Hybridization on Polymer Microparticles by Europium (III) Ion Fluorescence n Kaisa Ketomaki and Harri Lonnberg.n n 21. Measurement of the Sugar-Binding Specificity of Lectins Using Multiplexed Bead-Based Suspension Arrays n Kazuo Yamamoto, Fumiko Yasukawa, and Seiichiro Iton n 22. Nanotechnology: Moving from Microarrays Toward Nanoarrays n Hua Chen and Jun Li.
Klappentext
Microarray Technology, Volumes 1 and 2, present information in designing and fabricating arrays and binding studies with biological analytes while providing the reader with a broad deillegalscription of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments.
Among the topics discussed in Volume 1: Synthesis Methods, are matrices in the synthesis of microarrays, array optimization processes, array-based comparative genomic hybridization, 60-mer oligonucleotide probes, bifunctional reagents NTMTA and NTPAC, and high density arrays using digital microarray synthesis platforms. Other topics include multiplex ligation-dependent probe amplification (MLPA), hybridization conditions in situ-synthesized oligo arrays, peptide arrays, high density replication tools (HDRT), protocols for the quantification of oligo hybridization, glyco-bead arrays, and an investigation into the emerging nano technology.
Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.
Microarray Technology, Volumes 1 and 2, comprises a meticulous exploration into state-of-the-art methods and protocols for microarray technology. The volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad deillegalscription of microarray technology tools and their potential applications. The first volume deals with methods and protocols for the preparation of microarrays. The second volume details applications and data analysis, which is important in analyzing the enormous data coming out of microarray experiments. Microarray Technology, Volumes 1 and 2, provide ample information to all levels of scientists from novice to those intimately familiar with array technology.
