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The Neuroscience of Hallucinations
(Englisch)
Jardri, Renaud & Cachia, Arnaud & Thomas, Pierre & Pins, Delphine

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Produktbeschreibung

Gathers for the first time in one volume cutting-edge hallucination research from different areas of neuroscience

Presents a state-of-the-art review of the hallucinatory phenomenon, from molecular  to cognitive levels, including neuroimaging, computational, and innovative therapeutic aspects

Offers the vast multidisciplinary neuroscientific, psychological, and medical community an evidence-based model of the phenomenon


Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields.The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered:Hallucinations in the healthy individual.A pathophysiology of  transdiagnostic hallucinations including computational and connectivity modeling.Molecular mechanisms of hallucinogenic drugs.Structural and functional variations in the hallucinatory brain in schizophrenia.The neurodevelopment of hallucinations.Innovations in brain stimulation techniques and imaging-guided therapy.Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcomeThe Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.
Part I: The Basics of Hallucinations.- 1. An epistemological approach: history of concepts and ideas about hallucinations.- 2. Hallucinatory experiences in non-clinical populations.- 3. Hallucinations and other sensory deceptions in psychiatric disorders.- 4. Hallucinations associated with neurological disorders and sensory loss.- 5. Standardized assessment of hallucinations.- Part II: Cognitive Models of Hallucinations.- 6. The `bottom-up´ and `top-down´ components of the hallucinatory phenomenon.- 7. Speech processing and auditory verbal hallucinations.- 8. The role of memory retrieval and emotional salience in the emergence of hallucinations.- 9. Misattribution models (I): meta-cognitive believes and hallucinations.- 10. Misattributions models (II): source monitoring in hallucinating schizophrenia subjects.- 11. Time perception and discrimination in individuals suffering from hallucinations.- Part III: Neurobiological and Computational Models of Hallucinations.- 12. A neurodevelopmental perspective on hallucinations.- 13. Candidate genes involved in the expression of psychotic symptoms: a focus on hallucinations.- 14. Animal models and hallucinogenic drugs.- 15. Cannabis and hallucinations: studies in human subjects.- 16. Computational models of hallucinations.- Part IV: Brain-Imaging Insight into Hallucinations.- 17. Electrophysiological exploration of hallucinations (EEG, MEG).- 18. Structural imaging of the `hallucinating´ brain in schizophrenia.- 19. Functional brain imaging of auditory hallucinations: from self-monitoring deficits to co-opted neural resources.- 20. Functional brain imaging of hallucinations: symptom capture studies.- 21. Brain functioning when the voices are silent: aberrant default-mode in auditory verbal hallucinations.- 22. Connectivity issues of the `hallucinating´ brain.- Part V: Innovative Therapeutic Approaches of Hallucinations.- 23. Beyond monotherapy: the HIT-story.- 24. The psychopharmacology of hallucinations: ironic insights into mechanisms of action.- 25. Neuromodulation techniques to treat hallucinations.- 26. The future of brain stimulation to treat hallucinations.- 27. Perspectives in brain-imaging and computer-assisted technologies for the treatment of hallucinations.- Conclusion: Key-issues for future research in the neuroscience of hallucinations.

Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields.

 The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered: 

  • Hallucinations in the healthy individual.
  • A pathophysiology of  transdiagnostic hallucinations including computational and connectivity modeling.
  • Molecular mechanisms of hallucinogenic drugs.
  • Structural and functional variations in the hallucinatory brain in schizophrenia.
  • The neurodevelopment of hallucinations.
  • Innovations in brain stimulation techniques and imaging-guided therapy.

Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.

Renaud Jardri, M.D., Ph.D., is a child psychiatrist at the Lille University Medical Centre, France and associate faculty at the Group for Neural Theory, École Normale Supérieure, Paris, France.

Arnaud Cachia, Ph.D., is Associate Professor in Neurosciences at Université Paris Descartes, affiliated with the Center for Psychiatry and Neurosciences (INSERM, Ste-Anne Hospital) and the Laboratory for the Psychology of Child Development and Education (CNRS, Sorbonne).

Pierre Thomas, M.D., Ph.D., is Professor of Psychiatry at the Lille North of France University School of Medicine and Co-Research Director of the "Hallucinations & Delusions” team in the Functional Neuroscience and Disorders Laboratory (Lille, France).

Delphine Pins, Ph.D., is a CNRS researcher at the Functional Neurosciences and Disorders Laboratory (Lille, France), where she is Co-Research Director of the "Hallucinations & Delusions” team.


"Psychiatrists, neurologists, neuropsychologists,cognitive neuroscientists, clinical psychologists and pharmacologists willwelcome The Neuroscience of Hallucinations as a vital guide to the currentstate and promising future of their shared field. All researchers who areinterested in the brain and behavior will expand their knowledge base readingthis superb book. Neuroscience of Hallucinations represents an excellent,unique book, which is a real treat for all experts frm the field ofneuroscience, clinicians as well as basic scientists.” (Prof. Dalibor Karlovic,Alcoholism and Psychiatry Research, Vol. 51 (2), 2015)

"This volume provides a unique, comprehensive, multifaceted perspective on hallucinations. The editors have brought together an international cast of authors to provide 27 chapters, organized into 5 parts. ... Clinicians may particularly enjoy learning more about the assessment of hallucinations. ... The Neuroscience of Hallucinations provides a welcome and valuable collection of works on hallucinatory experience that is unprecedented in its scope.” (Robert M. Bilder, Archives of Clinical Neuropsychology, Vol. 26 (5), August, 2013)

"This superb book summarizes the state of neuroscience of the fascinating phenomenon of hallucinations. ... this is a welcome addition to psychiatry and clinical neuroscience. ... the editors and chapter authors have produced a brilliant review of the latest research in this burgeoning area. ... psychiatrists, psychologists, neuroscientists, and graduate students would benefit from this timely and comprehensive review. ... All researchers who are interested in the brain and behavior will expand their knowledge base reading this superb book.” (Michael Joel Schrift, Doody´s Book Reviews, May, 2013)


This book synthesizes the latest findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. Covers neuroimaging, interventions, therapies, drugs and more.
Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields.The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered:Hallucinations in the healthy individual.A pathophysiology of transdiagnostic hallucinations including computational and connectivity modeling.Molecular mechanisms of hallucinogenic drugs.Structural and functional variations in the hallucinatory brain in schizophrenia.The neurodevelopment of hallucinations.Innovations in brain stimulation techniques and imaging-guided therapy.Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcomeThe Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.
Part I: The Basics of Hallucinations.- 1. An epistemological approach: history of concepts and ideas about hallucinations.- 2. Hallucinatory experiences in non-clinical populations.- 3. Hallucinations and other sensory deceptions in psychiatric disorders.- 4. Hallucinations associated with neurological disorders and sensory loss.- 5. Standardized assessment of hallucinations.- Part II: Cognitive Models of Hallucinations.- 6. The 'bottom-up' and 'top-down' components of the hallucinatory phenomenon.- 7. Speech processing and auditory verbal hallucinations.- 8. The role of memory retrieval and emotional salience in the emergence of hallucinations.- 9. Misattribution models (I): meta-cognitive believes and hallucinations.- 10. Misattributions models (II): source monitoring in hallucinating schizophrenia subjects.- 11. Time perception and discrimination in individuals suffering from hallucinations.- Part III: Neurobiological and Computational Models of Hallucinations.- 12. A neurodevelopmental perspective on hallucinations.- 13. Candidate genes involved in the expression of psychotic symptoms: a focus on hallucinations.- 14. Animal models and hallucinogenic drugs.- 15. Cannabis and hallucinations: studies in human subjects.- 16. Computational models of hallucinations.- Part IV: Brain-Imaging Insight into Hallucinations.- 17. Electrophysiological exploration of hallucinations (EEG, MEG).- 18. Structural imaging of the 'hallucinating' brain in schizophrenia.- 19. Functional brain imaging of auditory hallucinations: from self-monitoring deficits to co-opted neural resources.- 20. Functional brain imaging of hallucinations: symptom capture studies.- 21. Brain functioning when the voices are silent: aberrant default-mode in auditory verbal hallucinations.- 22. Connectivity issues of the 'hallucinating' brain.- Part V: Innovative Therapeutic Approaches of Hallucinations.- 23. Beyond monotherapy: the HIT-story.- 24. The psychopharmacology of hallucinations: ironic insights into mechanisms of action.- 25. Neuromodulation techniques to treat hallucinations.- 26. The future of brain stimulation to treat hallucinations.- 27. Perspectives in brain-imaging and computer-assisted technologies for the treatment of hallucinations.- Conclusion: Key-issues for future research in the neuroscience of hallucinations.

"Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field. All researchers who are interested in the brain and behavior will expand their knowledge base reading this superb book. Neuroscience of Hallucinations represents an excellent, unique book, which is a real treat for all experts frm the field of neuroscience, clinicians as well as basic scientists." (Prof. Dalibor Karlovic, Alcoholism and Psychiatry Research, Vol. 51 (2), 2015)

"This volume provides a unique, comprehensive, multifaceted perspective on hallucinations. The editors have brought together an international cast of authors to provide 27 chapters, organized into 5 parts. ... Clinicians may particularly enjoy learning more about the assessment of hallucinations. ... The Neuroscience of Hallucinations provides a welcome and valuable collection of works on hallucinatory experience that is unprecedented in its scope." (Robert M. Bilder, Archives of Clinical Neuropsychology, Vol. 26 (5), August, 2013)

"This superb book summarizes the state of neuroscience of the fascinating phenomenon of hallucinations. ... this is a welcome addition to psychiatry and clinical neuroscience. ... the editors and chapter authors have produced a brilliant review of the latest research in this burgeoning area. ... psychiatrists, psychologists, neuroscientists, and graduate students would benefit from this timely and comprehensive review. ... All researchers who are interested in the brain and behavior will expand their knowledge base reading this superb book." (Michael Joel Schrift, Doody's Book Reviews, May, 2013)


Renaud Jardri, M.D., Ph.D., is a child psychiatrist at the Lille University Medical Centre, France and associate faculty at the Group for Neural Theory, École Normale Supérieure, Paris, France.

Arnaud Cachia, Ph.D., is Associate Professor in Neurosciences at Université Paris Descartes, affiliated with the Center for Psychiatry and Neurosciences (INSERM, Ste-Anne Hospital) and the Laboratory for the Psychology of Child Development and Education (CNRS, Sorbonne).

Pierre Thomas, M.D., Ph.D., is Professor of Psychiatry at the Lille North of France University School of Medicine and Co-Research Director of the "Hallucinations & Delusions" team in the Functional Neuroscience and Disorders Laboratory (Lille, France).

Delphine Pins, Ph.D., is a CNRS researcher at the Functional Neurosciences and Disorders Laboratory (Lille, France), where she is Co-Research Director of the "Hallucinations & Delusions" team.



Über den Autor

Renaud Jardri, M.D., Ph.D., is a child psychiatrist at the Lille University Medical Centre, France and associate faculty at the Group for Neural Theory, École Normale Supérieure, Paris, France.
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Arnaud Cachia, Ph.D., is Associate Professor in Neurosciences at Université Paris Descartes, affiliated with the Center for Psychiatry and Neurosciences (INSERM, Ste-Anne Hospital) and the Laboratory for the Psychology of Child Development and Education (CNRS, Sorbonne).
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Pierre Thomas, M.D., Ph.D., is Professor of Psychiatry at the Lille North of France University School of Medicine and Co-Research Director of the "Hallucinations & Delusions" team in the Functional Neuroscience and Disorders Laboratory (Lille, France).
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Delphine Pins, Ph.D., is a CNRS researcher at the Functional Neurosciences and Disorders Laboratory (Lille, France), where she is Co-Research Director of the "Hallucinations & Delusions" team.

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Inhaltsverzeichnis



Part I: The Basics of Hallucinations.- 1. An epistemological approach: history of concepts and ideas about hallucinations.- 2. Hallucinatory experiences in non-clinical populations.- 3. Hallucinations and other sensory deceptions in psychiatric disorders.- 4. Hallucinations associated with neurological disorders and sensory loss.- 5. Standardized assessment of hallucinations.- Part II: Cognitive Models of Hallucinations.- 6. The `bottom-up¿ and `top-down¿ components of the hallucinatory phenomenon.- 7. Speech processing and auditory verbal hallucinations.- 8. The role of memory retrieval and emotional salience in the emergence of hallucinations.- 9. Misattribution models (I): meta-cognitive believes and hallucinations.- 10. Misattributions models (II): source monitoring in hallucinating schizophrenia subjects.- 11. Time perception and discrimination in individuals suffering from hallucinations.- Part III: Neurobiological and Computational Models of Hallucinations.- 12. A neurodevelopmental perspective on hallucinations.- 13. Candidate genes involved in the expression of psychotic symptoms: a focus on hallucinations.- 14. Animal models and hallucinogenic drugs.- 15. Cannabis and hallucinations: studies in human subjects.- 16. Computational models of hallucinations.- Part IV: Brain-Imaging Insight into Hallucinations.- 17. Electrophysiological exploration of hallucinations (EEG, MEG).- 18. Structural imaging of the `hallucinating¿ brain in schizophrenia.- 19. Functional brain imaging of auditory hallucinations: from self-monitoring deficits to co-opted neural resources.- 20. Functional brain imaging of hallucinations: symptom capture studies.- 21. Brain functioning when the voices are silent: aberrant default-mode in auditory verbal hallucinations.- 22. Connectivity issues of the `hallucinating¿ brain.- Part V: Innovative Therapeutic Approaches of Hallucinations.- 23. Beyond monotherapy: the HIT-story.- 24. The psychopharmacology of hallucinations: ironic insights into mechanisms of action.- 25. Neuromodulation techniques to treat hallucinations.- 26. The future of brain stimulation to treat hallucinations.- 27. Perspectives in brain-imaging and computer-assisted technologies for the treatment of hallucinations.- Conclusion: Key-issues for future research in the neuroscience of hallucinations.


Klappentext

Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields.

The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered:

Hallucinations in the healthy individual.
A pathophysiology of  transdiagnostic hallucinations including computational and connectivity modeling.
Molecular mechanisms of hallucinogenic drugs.
Structural and functional variations in the hallucinatory brain in schizophrenia.
The neurodevelopment of hallucinations.
Innovations in brain stimulation techniques and imaging-guided therapy.

Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome
The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.




Gathers for the first time in one volume cutting-edge hallucination research from different areas of neuroscience

Presents a state-of-the-art review of the hallucinatory phenomenon, from molecular to cognitive levels, including neuroimaging, computational, and innovative therapeutic aspects

Offers the vast multidisciplinary neuroscientific, psychological, and medical community an evidence-based model of the phenomenon

Includes supplementary material: sn.pub/extras



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