I: Presidential Address.- 1. Evolving Concepts of Memory.- II: Genetic Determinants of Behavior.- 2. Chromosomal Studies in Psychiatry-Academic Address.- 3. Sex-Chromatin Variations in Institutionalized Females.- I. Sex Chromosome Anomalies in Hospitalized Schizophrenics, Adult Prisoners, Confined Juvenile Offenders, and Noninstitutionalized Volunteers.- II. Quantitative Differences Associated with Length of Confinement in State Mental Hospitals.- 4. Family History Studies: I. Two Types of Affective Disorders Separated According to Genetic and Clinical Factors.- 5. Chromosomal Mosaicism in the Human and Chromosomal Change in vitro.- 6. Hereditary Factors in Normal Personality Traits (as Measured by Inventories).- 7. Monozygotic Twin Similarity in Multiple Psychophysiologic Parameters and Measures.- 8. Sleep and Dream Patterns in Twins: Markov Analysis of a Genetic Trait.- 9. Phenomenological and Pharmacological Identity of Audiogenicsensitive State in Animals Treated with Methionine Sulfoximine and in Genetically Audiogenic-Seizure-Susceptible Animals.- Summary Report: Genes, Hormones, and Behavioral Critical Periods.- III: Clinical Research Reports.- 10. Altered Sensitivity to Centrally Active Drugs Following Lobotomy.- 11. A Controlled Study of Mental Disorders Associated with Epilepsy.- 12. Increase in Taste Acuity with Sympathetic Stimulation: The Relation of a Just-Noticeable Taste Difference to Systemic Psychotropic Drug Dose.- IV: Studies on LSD.- 13. Quantified LSD Effects on Ego Strength.- 14. Effects of LSD on Somatosensory and Visual Evoked Responses and on the EEG in Man.- 15. The Effects of Thiazesim, LSD-25, and Bilateral Lesions of the Amygdalae on the Release of a Suppressed Response.- V: Laboratory Research Reports.- 16. Etiology of the Stimulant Nature of the Schizophrenias.- 17. Experimental Myelopathy and Encephalopathy Induced by Actinomycin D.- 18. Biochemical Substrates for the Development of the Matured Evoked Potential.- Summary Report: Flow and Pressure Changes in the Circle of Willis: Model Studies.- VI: Developmental Studies.- 19. Sex Differences in Social Interaction between Infant Monkeys and Their Mothers.- 20. Instrumental Conditioning of Nutritive Sucking Behavior in the Newborn.- 21. Further Psychophysiological Studies of Retarded, Neurotic, Psychotic, and Normal Children.- VII: A. E. Bennett Award Papers.- 22. Neuropharmacological Studies and Postulates on Excitation and Depression in the Central Nervous System.- 23. The Chemical Plasticity of the Brain: The Role of Messenger RNA and Polysomes in Neural Function.- 24. Control of Epinephrine Synthesis by the Pituitary and Adrenal Cortex: Possible Role in the Pathophysiology of Chronic Stress.- In Memoriam.- Author Index.
Qualitative evaluations of buccal smear specimens have indicated an unusually high incidence of triple-X females in a hospitalized schizo phrenic population. Specimens from adult prisoners have also indicated an unusually high incidence of triple-X females. Studies of a population of confined juvenile offenders, on the other hand, have indicated an unusually high incidence of one-X females. No unusual indications were observed in a population of "normal" volunteer females. The data and their implications are discussed in context with previous observations. ACKNOWLEDGMENTS This study was made possible primarily by research grants from the Scottish Rite Committee on Research in Schizophrenia, The National Association for Mental Health, Inc. Additional support was provided by a grant from the National Institutes of Health, GRS-05563. The study has been supported by the State of Ohio, Department of Mental Hygiene and Correction, Division of Mental Hygiene. The author is particularly indebted to Edward N. Hinko, M.D., Regional Director of Research, whose advice and help made the present study possible. Invaluable cooperation and help have been received from the following administrators and their staffs: F. A. Lingl, M.D. (Cleve land Psychiatric Institute); Martha Wheeler (Ohio Reformatory for Women); M. B. McLane (Scioto Village); M. B. Holmes, M. D., and S. Caruso, M. D. (Massillon State Hospital); G. F. Ogram, M. D. (Athens State Hospital); C. Waltner, M. D. (Woodside Receiving Hospital); A. Mako, M. D. (Fairhill Psychiatric Hospital); and W. G. Stover, M. D.
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