Neuroendocrine Regulation of Gonadotropin Secretion.- Peptide-Steroid Interactions in the Modulation of the Hypothalamic-Pituitary Axis.- Localization of Neuroactive Substances in the Hypothalamus with Special Reference to Coexistence of Messenger Molecules.- Receptor-Weighted Mechanistic Approach to Analysis of the Actions of Estrogen and Progesterone on Gonadotropin Secretion.- The Steroid-Neuropeptide Connection in the Control of LHRH Secretion.- Transmembrane Signals and Intracellular Messengers Mediating LHRH and LH Secretion.- Regulation of Pulsatile Luteinizing Hormone Release During the Estrous Cycle and Pregnancy in the Rat.- Selective Modulation of FSH and LH Secretion by Steroids.- Role of Prolactin in the Regulation of Sensitivity of the Hypothalamic-Pituitary System to Steroid Feedback.- Regulation of Folliculogenesis and Ovulation.- Studies of the Periovulatory Interval in the In Vitro Perfused Ovary.- Significance of Angiogenic and Growth Factors in Ovarian Follicular Development.- Kinetic Aspects of Follicular Development in the Rat.- Animal Models for Study of Polycystic Ovaries and Ovarian Atresia.- Androgen-Induced Changes in Ovarian Granulosa Cells from Immature Rats In Vitro.- Estrogen-Producing Ovarian Granulosa Cells: Use of the Granulosa Cell Aromatase Bioassay (GAB) to Monitor FSH Levels in Body Fluids.- Receptor-Mediated Action Without Receptor Occupancy: A Function for Cell-Cell Communication in Ovarian Follicles.- Regulation of Corpus Luteum Function in Pregnancy.- Comparative Aspects of the Regulation of Corpus Luteum Function in Various Species.- Role of Estrogen and the Placenta in the Maintenance of the Rabbit Corpus Luteum.- Decidual Luteotropin Secretion and Action: Its Role in Pregnancy Maintenance in the Rat.- Role of Placental Lactogen and Prolactin in Human Pregnancy.- Regulation of Relaxin Secretion and its Role in Pregnancy.- Regulation of Testicular Cell Functions and Spermatogenesis.- Regulation of Mitochondrial and Microsomal Cytochrome P-450 Enzymes in Leydig Cells.- Demonstration of hCG Binding Sites and hCG Stimulated Steroidogenesis in Different Populations of Interstitial Cells.- Differentiation and Polarized Function of Sertoli Cells In Vitro.- Spermatogenesis In Vitro: Searching for In Vivo Correlates.- Hormonal Regulation of Sertoli Cell Function.- Short Papers.- Chronic Effects of Insulin and Insulin-Like Growth Factor-I on Steroidogenesis by Rat Leydig Cells.- Isolation and Characterization of Seminal Fluid Proteins that Bind Heparin.- Induction of 3?-Hydroxysteroid Dehydrogenase Activity by Insulin-Like Growth Factor-I in Primary Culture of Purified Leydig Cells.- The Effects of Low O2 and Antioxidants on Steroidogenic Capacity in Cultured Rat Leydig Cells.- Direct Effects of Hormones of the Hypothalamic-Pituitary-Thyroid Axis on Testicular Steroidogenesis in the Hamsters.- How does the Gonad Affect LHRH Secretion? Effects of Gonadectomy on LHRH Release from Median Eminence Nerve Terminals Incubated In Vitro and on LHRH Concentration in Hypophyseal Portal Blood.- Orchidectomy Induces Temporal and Regional Changes in the Synthesis and Processing of the LHRH Prohormone in the Rat Brain.- Pulsatile Hormone Secretion Late in the Luteal Phase of Normal and Infertile Women During Diurnal Hours.- LH and Estradiol Secretion after HCG and GNRH Treatments in Gilts.- Several GnRH Stimulation Frequencies Differentially Release FSH and LH from Isolated, Perfused Rat Anterior Pituitary Cells.- Opioid Modulation of Follicle Stimulating Hormone (FSH) and Prolactin (PRL) Secretion in the Postpartum Sow.- On the Site of Action of the Estradiol-Induced Release of Luteinizing Hormone (LH) in Pigs.- Induction of Follicular Cysts in Rat Ovaries by Prolonged Administration of Human Chorionic Gonadotropin.- Paracrine Control of 3?-Hydroxysteroid Dehydrogenase, 17,20-Lyase and Aromatase Enzyme Systems in Porcine Thecal Cells.- Stimulation of Intracellular Free Ca2+ by Luteinizing Hormone in Isolated Bovine Luteal Cells.- The Effect of Prostaglandin F2? on Mitochondrial Election Dense Inclusions and Secretory Granules of the Bovine Large Luteal Cell During Late Pregnancy.- In Vitro Production of Angiotropic Factor by Bovine Corpus Luteum: Partial Characterization of Activities that are Chemotactic and Mitogenic for Endometrial Cells.- Action of Progesterone and RU38486 on Protein Synthesis in Rat Placenta.- The Intraovarian Effect of Progesterone on Follicle Development in the Rabbit Ovary.- The Relationships of Oocyte Quality and Follicular Fluid Prolactin and Progesterone in Superovulated Beef Heifers with and without Norgestomet Implants.- Coordinated Receptor Regulation in Ovarian Granulosa Cells.- Ovarian and Decidual Relaxins in Human Pregnancy.- The Effect of Prostaglandin F2? on Relaxin Release Differs in the Cyclic and Pregnant Sow.- Levels of Follicle Regulatory Protein in Regular Menstruating and Amenorrheic Patients.- Ovarian Follicular Fluid Peptide (OFFP): Effects on Follicular Maturation, Ovulation and Luteinization in Mice and Marmosets.- Chemical Characteristics of Follicular Glycosaminoglycans.- On the Intrinsic Ovarian Control of the Developmental Transition from Primordial to Primary Follicle.- Stereochemical Complementarity of Antiestrogens and DNA.- Contributors.
Rapid advances have taken place in various aspects of reproductive biology during the last decade. These advances have centered around several organ systems that comprise the reproductive system and encompass molecular events and structure-function relationships. It becomes important to review these advances in knowledge, at periodic intervals, with respect to feedback systems and regulatory loops that control reproductive processes in vivo. Towards this end, a workshop entitled "Functional Correlates of Hormone Receptors in Reproduction" sponsored by the National Institute of Child Health and Human Development and the Reproductive Biology Study Section of the Division of Research Grants, National Institutes of Health was held in October 1980. The proceedings of the workshop were published by Elsevier Biomedical/New York. This workshop was followed by two workshops sponsored by the Reproductive Biology Study Section of the Division of Research Grants, National Institutes of Health entitled "Role of Peptides and Proteins in Control of Reproduction" in February 1982 and published by Elsevier Biomedical and "Molecular and Cellular Aspects of Reproduction" in October 1985 and published by Plenum Press. It was, therefore, timely to review the current state of knowledge regarding the regulation of ovarian and testicular function by bringing together scientists working in separate and discrete aspects of reproduction to review the functional implications of their research on the regulation of function within the same tissue and also in relationship to feedback systems and regulatory loops with other tissues.
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