Section I.- Introductory Remarks: Ruminations on Ovarian Function.- Section II.- Follicular Growth in the Rat: A Reevaluation of the Roles of FSH and LH.- LH-Induced Desensitization of the Adenylyl Cyclase System in Ovarian Follicles.- Gonadal LH receptors: Resolution from Adenylate Cyclase and Transfer to Heterologous Cells.- Prolactin Control of Receptor for Estradiol in Corpora Lutea of Pregnant Rats.- Chairperson's Remarks.- Lateral Mobility and Internalization of Hormone Receptors to Human Chorionic Gonadotropin in Cultured Rat Granulosa Cells.- FSH Stimulation of Mucopolysaccharide Synthesis in Rat and Porcine Ovary.- Immunologic Impairment of ?5-3B Hydroxysteroid Dehydrogenase and Its Effect on Ovarian Function: The Use of a Purified Enzyme.- Receptors for Gonadotrophins in the Ovine Follicle During Growth and Atresia.- Effect of Oestradiol-17? and Gonadotrophins on Prostaglandin Production by Pre-Ovulatory Pig Follicles Superfused in vitro.- LH-Stimulated cAMP Formation in Rat Granulosa Cells During Follicular Maturation - a Non-Refractory Response.- Effect of the Administration of an Ovulatory Dose of HCG on the Subcellular Distribution of Follicular Protein Kinase.- Structural Analysis of Granulosa Cells from Human Ovaries in Correlation with Function.- Regulation of LH(hCG)-Receptor and Adenylate Cyclase in Luteinizing Granulosa Cells.- Changes in Responsiveness of Porcine Granulosa Cells to Prostaglandins and Luteinizing Hormone in Terms of Cyclic-AMP Accumulation During Follicular Maturation.- Some Morphological and Functional Characteristics of Cells of the Porcine Theca Interna in Tissue Culture.- The Control of Ovulation in the Cow by Prostaglandin Inhibitor.- Section III.- Steroidal Modulation of Steroid Secretion in vitro: An Experimental Approach to Intra-Follicular Regulatory Mechanisms.- On the Mechanism of Prolactin Stimulation of Steroidogenesis.- Steroid Secretion by Perifused Ovarian Follicles of Immature, PMSG-Treated Immature, and Mature Rabbits.- Effects of Follicular Development on the Ability of Cultured Porcine Granulosa Cells to Convert Androgens to Estrogens.- Testosterone Synthesis by Chicken Follicular Cells.- Modulation of Thecal Progesterone Secretion by Estradiol-17?.- Chairperson's Remarks.- Steroid Secretion by Ovarian Follicles of Rabbits in Different Reproductive States.- Hormone Requirements for Long-Term Maintenance of Rat Granulosa Cell Cultures.- Long-Term Perfusion of Rabbit Ovarian Follicles.- Estrogen Inhibits Porcine Thecal Androgen Production in vitro.- Antral Follicular and Interstitial Contributions to Progesterone Secretion in the Proestrous Hamster.- Section IV.- Meiotic Maturation of Mouse Oocytes in vitro.- Mammalian Oocyte Maturation: Model Systems and Their Physiological Relevance.- Action of Porcine Follicular Fluid Oocyte Maturation Inhibitor in vitro: Possible Role of the Cumulus Cells.- Relationship Between Steroidogenesis and Oocyte Maturation in Rat Graafian Follicles Cultured in vitro.- Chairperson's Remarks.- The Somatic-Germ Cell Complex.- Rapid Oocyte Death Prior to and at Puberty in Neonatally Thymectomized Mice.- Maturation and Atresia of Human Oocytes in vivo.- Section V.- Follicular Non-Steroidal Regulators.- The Influence of Follicular Fluid on Progesterone Secretion by Porcine Granulosa Cells in vitro.- Inhibition of in vivo and in vitro FSH Secretion by Steroid-Free Hamster Ovarian Extracts.- The Differential Ability of Porcine Follicular Fluid to Suppress Serum FSH in Female Rats from 6 Days of Age to Adulthood.- Evidence for the Presence of a Low Molecular Weight Follitropin Binding Inhibitor in Bovine Follicular Fluid.- Chairperson's Remarks.- Inhibition by Follicular Fluid of Luteinizing Hormone-Sensitive Adenylate Cyclase in Ovarian Plasma Membranes.- Inhibitory Effect of Charcoal-Treated Porcine Follicular Fluid upon Serum FSH Levels and Follicular Development in the Rhesus Monkey.- Follicular Fluid Inhibition of Ovulation.- Modulation of Pit
The purpose of this volume, the proceedings of the Second Ovarian Workshop, is to review the state of the art in ,the field of ovarian follicular and corpus luteum function. This workshop was sponsored by the Center of Population Research, Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland. We also acknowledge the support of The Channing-Weinberg Company, Mr. Henry Burckhardt, The Merck Institute for Experimental Research, The Ortho Pharmaceutical Company, The Expanded Program for Human Reproduction of the World Health Organization, and The University of Miami. We thank the organizing committee consisting of Drs. Hans Lindner, Georgianna Jagiello, Neena Schwartz, Rees Midgley, Gil Greenwald, Andrew Nalbandov, Sheldon Segal, Julia Labotsky, and Griff Ross for their generous assistance in setting up the program. We also thank the chairpersons of each session for their skillful work and for using their expertise in keeping the discussions to the point. We also are grateful to them for editing the written discussions. Chairpersons included Drs. Robert J. Ryan, Roy O. Greep, Allen W. Schuetz, Neena B. Schwartz, John M. Marsh, John W. Wilks, Hans R. Lindner, and Scheldon J. Segal. Special thanks go to all the invited speakers, discussants, participants and particularly Dr. Irving Rothchild for his summing up remarks. The above organization of Ms. Betty Howard and her staff is gratefully acknowledged. The above secretarial assistance of Ms. Gail Williams, Ms. Evelyn Wisowaty, Ms. Theda Smith and Ms.
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