In Single Molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.
Explores sophisticated advances in powerful new analytical, computational, and imaging methods
Cover ways in which single-molecule methods can be applied to studying protein function
Lays the foundation for additional research to monitor processes within living cells at high resolution and define the complex networks of interactions which regulate cellular function