Comprehensive critical reviews and original research papers from the 2011
Proceedings of the International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
Provides an in-depth analysis of data on cell surface macromolecules in cellular function
Covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell–matrix interaction
Prof. Perumana R. Sudhakaran is currently the Dean of the School of Biological Sciences and Professor of Biochemistry, Central University of Kerala, Kasargod, India. His major area of research is cell extracellular matrix interaction and cell signaling.Prof. Avadesha Surolia is currently the Director of the National Institute of Immunology, New Delhi and a Professor of Molecular Biophysics at the Indian Institute of Science, Bangalore, India. His major areas of research include structure and function of lectins, orientation and dynamics of cell surface carbohydrate receptors, protein folding and quality control in the endoplasmic reticulum.
Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell–matrix interaction.
Preface
Chapter 1. Glycomics: An overview of the complex glycocode
Chapter 2. Structural Glycomic Approaches to Molecular Recognition Events on Cell Surfaces
Chapter 3. Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis
Chapter 4. Chondroitin sulfate-specific novel hydrolase in human
Chapter 5. Identification of endothelial cell surface carbohydrate-binding receptors by carbohydrate ligand mimicry peptides.
Chapter 6. Lysosomal enzyme sorting receptors – Where did they first appear in the animal kingdom?
Chapter 7. Endoplasmic reticulum targeted Bcl-2 inhibitable mitochondrial fragmentation initiates ER stress induced cell death
Chapter 8. Interactions between Caveolin-1and Sphingolipids and their functional relevance
Chapter 9. Cell Membrane Repair Pathway Involves Sensing of Dynamics of Caveolae and Caspase-1
Chapter 10. Angiogenic Response of Endothelial Cells to Fibronectin
Chapter 11. Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models
Chapter 12. Advanced Fret Methodologies: Protein Lipid Selectivity detection and Quantification
Chapter 13. Mechanism of GPCR-directed Autoantibodies in Diseases
Chapter 14. Role of Membrane Cholesterol in Leishmanial Infection
Chapter 15. How Intact is the Basement Membrane? Role of MMPs
Chapter 16. Apoptosis of Breast Cancer Cells: IX. Modulation of Genes for Glycoconjugate Biosynthesis and Targeted Drug Delivery
Chapter 17. Altered expression of sialidases in human cancer
Chapter 18. Poly-ADP-ribosylation of vascular endothelial growth factor and its implications on angiogenesis.
Chapter 19. Sphingolipid Binding Domain in the Serotonin1A Receptor
Chapter 20. Withanolide-D, carrying the baton of Indian Rasayana herb as a lead candidate of anti-leukemic agent in modern medicine
Chapter 21. Engineered glucose to generate a spectroscopic probe for studying carbohydrate biology
Chapter 22. Changes in sialic acid content of jelly coat in pesticide exposed frog eggs and its influence on fertilization
The 2011 international symposium on the "Biochemical Role of Eukaryotic Cell surface Macromolecules” (Trivandrum, India - Jan 2011) covered topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell–matrix interaction. Contributions from this meeting are presented this volume, providing an in-depth analysis of data on cell surface macromolecules in cellular function and their alteration associated with pathological conditions. All contributions are either comprehensive critical reviews or original research papers and cover the most relevant and recent topics related to functional role of cell surface molecules.
Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell matrix interaction.
Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell-matrix interaction.
Glycomics: An overview of the complex glycocodec.- Structural Glycomic Approaches to Molecular Recognition Events on Cell Surfaces.- Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis.- Chondroitin sulfate-specific novel hydrolase in human
Identification of endothelial cell surface carbohydrate-binding receptors by carbohydrate ligand mimicry peptides.- Lysosomal enzyme sorting receptors - Where did they first appear in the animal kingdom?.- Endoplasmic reticulum targeted Bcl-2 inhibitable mitochondrial fragmentation initiates ER stress induced cell death.- Interactions between Caveolin-1and Sphingolipids and their functional relevance.- Cell Membrane Repair Pathway Involves Sensing of Dynamics of Caveolae and Caspase-1.- Angiogenic Response of Endothelial Cells to Fibronectin.- Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models.- Advanced Fret Methodologies: Protein Lipid Selectivity detection and Quantification
Mechanism of GPCR-directed Autoantibodies in Diseases.- Role of Membrane Cholesterol in Leishmanial Infection.- How Intact is the Basement Membrane? Role of MMPs.- Apoptosis of Breast Cancer Cells: IX. Modulation of Genes for Glycoconjugate Biosynthesis and Targeted Drug Delivery.- Altered expression of sialidases in human cancer
Poly-ADP-ribosylation of vascular endothelial growth factor and its implications on angiogenesis.- Sphingolipid Binding Domain in the Serotonin1A Receptor.- Withanolide-D, carrying the baton of Indian Rasayana herb as a lead candidate of anti-leukemic agent in modern medicine.- Engineered glucose to generate a spectroscopic probe for studying carbohydrate biology.- Changes in sialic acid content of jelly coat in pesticide exposed frog eggs and its influence on fertilization.
Über den Autor
Prof. Perumana R. Sudhakaran is currently the Dean of the School of Biological Sciences and Professor of Biochemistry, Central University of Kerala, Kasargod, India. His major area of research is cell extracellular matrix interaction and cell signaling.
Prof. Avadesha Surolia is currently the Director of the National Institute of Immunology, New Delhi and a Professor of Molecular Biophysics at the Indian Institute of Science, Bangalore, India. His major areas of research include structure and function of lectins, orientation and dynamics of cell surface carbohydrate receptors, protein folding and quality control in the endoplasmic reticulum.
Inhaltsverzeichnis
Glycomics: An overview of the complex glycocodec.- Structural Glycomic Approaches to Molecular Recognition Events on Cell Surfaces.- Chondroitin sulfate E-type structure at tumor cell surface is involved in experimental metastasis.- Chondroitin sulfate-specific novel hydrolase in human
Identification of endothelial cell surface carbohydrate-binding receptors by carbohydrate ligand mimicry peptides.- Lysosomal enzyme sorting receptors - Where did they first appear in the animal kingdom?.- Endoplasmic reticulum targeted Bcl¿2 inhibitable mitochondrial fragmentation initiates ER stress induced cell death.- Interactions between Caveolin-1and Sphingolipids and their functional relevance.- Cell Membrane Repair Pathway Involves Sensing of Dynamics of Caveolae and Caspase-1.- Angiogenic Response of Endothelial Cells to Fibronectin.- Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models.- Advanced Fret Methodologies: Protein Lipid Selectivity detection and Quantification
Mechanism of GPCR-directed Autoantibodies in Diseases.- Role of Membrane Cholesterol in Leishmanial Infection.- How Intact is the Basement Membrane? Role of MMPs.- Apoptosis of Breast Cancer Cells: IX. Modulation of Genes for Glycoconjugate Biosynthesis and Targeted Drug Delivery.- Altered expression of sialidases in human cancer
Poly-ADP-ribosylation of vascular endothelial growth factor and its implications on angiogenesis.- Sphingolipid Binding Domain in the Serotonin1A Receptor.- Withanolide-D, carrying the baton of Indian Rasayana herb as a lead candidate of anti-leukemic agent in modern medicine.- Engineered glucose to generate a spectroscopic probe for studying carbohydrate biology.- Changes in sialic acid content of jelly coat in pesticide exposed frog eggs and its influence on fertilization.
Klappentext
Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell-matrix interaction.
Comprehensive critical reviews and original research papers from the 2011
Proceedings of the International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
Provides an in-depth analysis of data on cell surface macromolecules in cellular function
Covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell-matrix interaction
Includes supplementary material: sn.pub/extras
