AcknowledgementsPrefacePart 1: Nucleolar Structure and Organization1. Structural organization of the nucleolus as a consequence of the dynamics of ribosome biogenesisDanièle Hernandez-Verdun2. The dynamic proteome of the nucleolusFrançois-Michel Boisvert, Yasmeen Ahmad, Angus I. Lamond3. The Structure of rDNA ChromatinPeter C McKeown, Peter J Shaw4. The epigenetics of the nucleolus: structure and function of active and silent ribosomal RNA genesRaffaella Santoro5. UBF, an Essential Player in Maintenance of Active NORs and nucleolar formationAlice Grob, Christine Colleran, Brian McStayPart 2: Role of the Nucleolus in Ribosome Biogenesis6. The RNA Polymerase I Transcription MachineryRenate Voit, Ingrid Grummt7. Small Ribonucleoproteins in Ribosome BiogenesisFranziska Bleichert, Susan Baserga8. Crosstalk between ribosome synthesis and cell cycle progression and its potential implications in human genetic diseaseMarie Gérus, Michèle Caizergues-Ferrer, Yves Henry, Anthony Henras9. The multiple properties and functions of nucleolinRong Cong, Sadhan Das, Philippe Bouvet10. The multifunctional nucleolar protein nucleophosmin/NPM/B23 and the nucleoplasmin family of proteinsShea Ping Yip, Parco M. Siu, Polly H.M. Leung, Yanxiang Zhao, Benjamin Y.M Yung11. Structure and function of NOPP140 and treacleFang He, Patrick DiMarioPart 3: Novel Functions of the Nucleolus12. Chapter 12. The Role of the Nucleolus in the Stress ResponseLaura A. Tollini, Rebecca A. Frum, Yanping Zhang13. New Frontiers in Nucleolar Research - Nucleostemin and Related ProteinsRobert Tsai14. Viruses and the NucleolusDavid Matthews, Edward Emmott, Julian Hiscox15. Assembly of Signal Recognition Particles in the NucleolusMarty Jacobson16. Relationship of the Cajal Body to the NucleolusAndrew Gilder, Michael Hebert17. Role of the Nucleolus in HIV Infection and TherapyJerlisa Arizala, John Rossi
Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.
Covers recent discoveries on novel functions of the nucleolus.Emphasizes nucleolar proteins while also including the crucial importance of nucleic acids.Includes chapters on nucleolar ultrastructure, the locations and dynamics of nucleolar components, and on regulatory systems.