Part 1 - ACL Injury: The Clinical ProblemChapter 1 ACL Injury Epidemiology Patrick Vavken and Martha M. MurrayChapter 2 History of ACL Treatment and Current Gold Standard of Care
Martha M. MurrayChapter 3 ACL Clinical Outcomes Carolyn Hettrich and Kurt P. SpindlerChapter 4 ACL Treatment in the Skeletally Immature PatientPatrick Vavken and Martha M. MurrayPart 2 - ACL Injury: The Biologic ProblemChapter 5 The Biology of the Normal ACLMartha M. Murray and Braden C. FlemingChapter 6 The Role of Inflammation and Blood Cells in Wound HealingLinda H. Chao and Martha M. MurrayChapter 7 The ACL Response to InjuryMartha M. MurrayChapter 8 The Biology of Impaired Healing of Joint IssuesMartha M. MurrayPart 3 - Translational Medicine: In Vitro and In Vivo ModelsChapter 9 Translational MedicinePatrick VavkenChapter 10 In Vitro Models of ACL InjuryPatrick Vavken and Braden C. FlemingChapter 11 In Vivo Models of ACL Injury (Central Defect, Porcine, Ovine, Canine) Benedikt Proffen and Martha M. MurrayChapter 12 Tissue Engineering of Ligaments and TendonsPatrick Vavken and Martha M. MurrayChapter 13 Outcome Assessment for ACL Tissue EngineeringPatrick Vavken, Martha M. Murray, and Braden C. FlemingPart 4 - Stimulating Healing of the ACL Using Tissue EngineeringChapter 14 Scaffolds and Biologic Additives for ACL SurgeryRyu Yoshida and Martha M. MurrayChapter 15 Use of Biologics to Treat Partial ACL TearsMartha M. MurrayChapter 16 Can We Get a Complete ACL Tear to Heal?Carla Haslauer and Martha M. MurrayChapter 17 The Effects of Platelets and Their Concentration on ACL Healing Patrick VavkenChapter 18 The Effects of WBCs and RBCs on Ligament Healing Linda Chao and Martha M. Murray Chapter 19 Safety of the Bioenhanced RepairElise M. Magarian and Martha M. MurrayChapter 20 Re-Innervation and Revascularization in Engineered ACL HealingBenedikt Proffen and Martha M. MurrayChapter 21 Bio-enhancement of ACL Graft HealingBraden C. FlemingChapter 22 The Effects of Age and Skeletal Maturity on Healing of the Anterior Cruciate LigamentLinda H. Chao and Martha M. Murray
The new age of biologic treatment of the ACL is coming. In The ACL Handbook: Knee Biology, Mechanics, and Treatment, the authors cover the past and current state of ACL injuries and treatment, and then introduce and explain the key concepts for understanding the new biologic approach to ACL treatment. The use of factors to enhance graft healing are reviewed, as well as an in-depth review of the science of platelet-rich plasma and its cellular components (platelets, white cells, and plasma). Chapters on in vitro models for science as well as the advantages and disadvantages of animal models for ACL research are included, as are chapters on the new technique of bio-enhanced ACL repair. All are discussed in easily readable text aimed at anyone with an interest of what is coming next in ACL surgery.
A truly innovative integrative multidisciplinary approach
Consolidates the knowledge on the issue of ACL injuries and repair
Cutting-edge developments for ACL treatment are relevant for a wide variety of specialists