Tumor Biology.- 1. Expression Genetics in Cancer Research, Prognosis, and Therapy.- 2. Patterns of Chromosomal Imbalances in Carcinomas of the Respiratory Tract.- 3. Inhibition of Tumorigenesis in a Murine B-Cell Lymphoma Transplant Model by c-Myc Complementary Oligonucleotides.- 4. Telomerase Inhibition by Induced Expression of Antisense RNA.- 5. Ex Vivo and in Vivo IGF-I Antisense RNA Strategies for Treatment of Cancer in Humans.- 6. Use of the IGF-I Antisense Strategy in the Treatment of the Hepatocarcinoma.- 7. Functional Involvement of CD44, a Family of Cell Adhesion Molecules, in Immune Responses, Tumour Progression and Haematopoiesis.- 8. The Influence of CD44 Splice Variants to the Outcome of Patients with Oral Squamous Cell Carcinoma.- 9. Control of Tumor Growth via Inhibition of Tumor Angiogenesis.- 10. Expression of Collagenase-3 (MMP-13) by Tumor Cells in Squamous Cell Carcinomas of the Head and Neck.- 11. High Level Expression of Tissue Inhibitors of Metalloproteinases-1,-2 and -3 in Melanoma Cells Achieved by Adenovirus Mediated Gene Transfer.- 12. Tissue Inhibitor of Metalloproteinase Expression: A Target for Gene Therapy in Renal Cell Carcinoma.- 13. In Vivo Tumor Suppressor Effect of Retrovirus-Mediated Gene Transfer of the Adenovirus E1a Gene.- 14. Antitumor Effect of E1B Defective Adenoviruses in Human Malignant Cells.- 15. Inhibition of Human Pancreatic Cancer Growth by the Adenovirus-Mediated Introduction of a Novel Growth Suppressing Gene, tob, in Vitro.- Chemogene Therapy.- 16. Intratumoral Injection of Encapsulated Cells Producing an Oxazaphosphorine Activating Cytochrome P450 for Targeted Chemotherapy.- 17. Sensitisation of Human Ovarian Cancer Cells to Killing by the Prodrug CB1954 Following Retroviral or Adenoviral Transfer of the E. coli Nitroreductase Gene.- 18. HSV-1 Thymidine Kinase Gene Therapy for Peritoneal Carcinomatosis.- 19. Characteristics of Cytosine Deaminase-5-Fluorocytosine System: Enhancement of Radiation Cytotoxicity and Bystander Effect.- 20. Potentiation of the Bystander Effect by Immunization Combined with Suicide Gene Therapy.- 21. Another Mechanism Causing the Bystander Effect Besides the Gap Junction's Role during the Glioma Gene Therapy with HSV-TK/GCV System.- 22. In Vivo Evaluation of a Drug-Inducible Vector System for the Combined Gene- and Chemotherapy of Cancer.- 23. IL-2 Gene Transfer for Chemosensitization of Multidrug-Resistant Human Colon Carcinoma Cells.- 24. Cytotoxic Effect of Binar Cisplatin Immunoconjugate.- 25. Dietary Indole Derivatives Induce Apoptosis in Human Breast Cancer Cells.- Tumor Immunology.- 26. Overcoming T Cell Ignorance by Providing Costimulation: Implications for the Immune Response against Cancer.- 27. Immune Cells in the Tumor Microenvironment: Mechanisms Responsible for Functional and Signaling Defects.- 28. Dendritic Cells Prevent CD95 Mediated T Lymphocyte Death through Costimulatory Signals.- 29. Interleukin-10 Inhibits the Immune Stimulatory Potential of Melanoma Cells Retrovirally Transduced with Human B7.1 or B7.2.- 30. Immunosuppressive Cells in Bone Marrow of Patients with Stomach Cancer.- 31. Induction of Antigen-Specific T Cells by Allogeneic CD80 Transfected Human Carcinoma Cells.- 32. IL-12-Activated NK Cells Recognize B7 Costimulatory Molecules on Tumor Cells and Autologous Dendritic Cells.- 33. Effects of Altered Antigen Processing on T-Cell Responses toward Murine T-Lymphomas.- 34. Cancer Gene Therapy with a Heat Shock Protein Gene.- 35. Heat Shock Protein (HSP72) Surface Expression Enhances the Lysis of a Human Renal Cell Carcinoma by IL-2 Stimulated NK Cells.- 36. Identification of Epitopes for CTCL-Specific Cytotoxic T Lymphocytes.- 37. Effects of Altered Antigen Processing on H-2Dk Mediated NK Inhibition in a Murine T Lymphoma Model.- 38. Recognition of Melanoma-Associated Peptides by Peripheral Blood Mononuclear Cells of Ocular Melanoma Patients.- 39. Detection of Micrometastasis in 31 Patients with Breast Cancer by RT-
The book provides a comprehensive overview of the current state, and the new concepts for the future directions of modern cancer therapy. Bringing together all the relevant aspects from basic and applied science, and the clinical experiences of this new direction in medicine, it is an up-to-date summary of the activities in the field and will be the basis for evaluating future progress in this area.
Springer Book Archives