Neurological disorders cause untold suffering and financial burden to hundreds of thousands of people, not only to the patients, but also the relatives and society. As of today, though numerous scientists and clinicians have devoted their efforts to understand and combat these diseases, there is still no cure or satisfactory solution to the problems. Furthermore, the brain is the most essential organ of a human being. Realizing the importance of the brain, the president of the United States, George Bush, declared the 90s as the Decade of the Brain in January, 1992. Being in neuroscience research for almost three decades, I initiated, planned and organized the first international neuropharmacology symposium. After long negotiation and fund raising, with the assistance and moral support of Dr. Abel Lajtha, director ofthe Center ofNeurochem istry in New York, USA, we finally successfully put the program together. The Sun Yat-sen Foundation in China supported all the local expenses of the symposium and Sun Yat-sen University of Medicine in Guangzhou, China served as host organization. The symposium was held in Guangzhou, China, November 9-11,1992, the eve of Dr. Sun Yat-sen's birthday. Dr. Sun Yat-sen was born in Cui Heng Cun, on the outskirts of Guangzhou, China on November 12, 1866. He finished his high school education in the British and American Christian school in Honolulu, where he was exposed to Western influence. He had been long frustrated and discontented with the backwardness and corruption of the Ching Dynasty.
Perspective of Neurochemistry in Neurological Disorders.- Selegiline Induces "Trophic-Like" Rescue of Dying Neurons without Mao Inhibition.- Aliphatic Propargylamines, a New Series of Potent Selective, Irreversible Non-Amphetamine-Like MAO-B Inhibitors.- Medical Treatment of Parkinson's Disease.- Neuropharmacological Effects of (-)-Stepholidine and Its Analogues on Brain Dopaminergic System.- Neurotoxicity of MPTP and Uptake of MPPT into Dopamine and Norepinephrine Neurons in Mice.- Linopirdine.- Differential Changes in Regional Brain Ganglioside and Neutral Glycosphingolipid Contents in Alzheimer's Disease.- Action of Organophosphate Anticholinesterases on the Three Conformational States of Nicotinic Receptor.- Purification and Characterization of a Novel Neurotoxin-Kappa Bungarotoxin.- Development of Antidepressant Drugs.- The Identification of Heterogeneity of 5-HT Receptors with [H]Rs-42358-197.- Advances in Clinical Research on Common Mental Disorders with Computer Controlled Electro-Acupuncture Treatment.- The Importance of Glutamate Receptors in Brain Ischemia.- Biochemical Study of the Postischemic Neuronal Damage.- Effects of Ilexonin A on Circulatory Neuroregulation.- Study on Cerebrovascular Disease of the Elderly in China.- Cellular Physiology of Epileptogenic Phenomena.- The Clinical Pharmacology of Antiepileptic Drugs.- Hemodynamic Actions of Huatuo Reconstruction Pill on Anesthetized Animals.- Treatment of Affective Disorders.- Studies of Diagnosis and Pathogenesis of Wilson's Disease.- Evidence for Presynaptic Damage in Myasthenia Gravis.
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