for Volume I.- I. Overview.- 1. Health Care of the Aging: Trends, Dilemmas, and Prospects for the Year 2000.- 2. The Next Twenty Years: Medical Science and the Practice of Geriatrics.- II. Basic Mechanisms of Biologic Aging.- 3. The Biology of Aging and the Quality of Later Life.- 4. Extending the Mammalian Life Span.- 5. Aging Humans and Aging Cells.- 6. A Progress Report on Neurochemical and Neuroendocrine Regulation in Normal and Pathologic Aging.- 7. New Approaches to Alzheimer's Disease: Neurotrophic Factors.- III. Neurochemistry of Aging and Age-Related Diseases.- 8. Neurochemistry of the Aging Brain and Senile Dementia.- 9. Brain Neurotransmitters in Normal Aging.- 10. Neuropeptides in Human Aging and Dementia.- 11. Receptor-Mediated Alterations of Central Monoaminergic Transmission in Aged Wistar Rats.- 12. Dopamine Receptors: Antiparkinsonian Activity and Molecular Mechanisms.- 13. Prolactin Studies in Senile Dementia of the Alzheimer Type.- 14. Prospects for Synergistic Drug Combinations for the Treatment of Senile Amnesias.- 15. Effects of Aging and Hypertension on Cerebral Blood Flow and Autoregulation in Normal Subjects and CVD Patients.- IV. Imaging Techniques.- 16. Imaging Techniques of the Aging Brain.- 17. Computerized Tomography (CT) and Positron Emission Tomography (PET) in Normal and Pathologic Aging.- V. Experimental Neuropathology.- 18. Cholinergic Deficiencies in Senile Dementia of the Alzheimer Type.- 19. Noncortical Transmitter-Specific Neurons in Senile Dementia of the Alzheimer Type.- 20. Neuropathology of the Aging Brain and Dementia of the Alzheimer Type.- VI. Prevention and Treatment of Physical Disorders.- 21. Interaction of Aging and Disease.- 22. Rational and Successful Health Care of Tomorrows Elderly: An Academic Perspective.- VII. Interface of Psychiatry and Medicine.- 23. Psychiatry versus Medicine: Am I My Brothers Keeper?.- 24. Toward an Interface of Mental and Physical Health Phenomena in Geriatrics: Clinical Findings and Questions.- VIII. Pharmacotherapy of Mental Illness in the Elderly.- 25. Pharmacotherapy of Mental Disorders of Old Age.- 26. Considerations for Treating the Elderly with Psychotropic Medications.- 27. Rationale for the Use of Therapeutic Agents in Affective Disorders (AD) and Senile Dementia of the Alzheimer Type (SDAT).- 28. Prospects for the Development of Safer Antipsychotic Agents for the Treatments of the Elderly.- 29. Prospects for Safer Pharmacologic Treatment of Affective Disorders in the Elderly.- IX. Dihydroergotoxine Mesylate (Hydergine).- 30. Hydergine: Interaction with Neurotransmitter Systems in the Central Nervous System.- 31. Implications of Long-Term Study of Hydergine in Elderly Patients with Chronic Senile Cerebral Insufficiency.- 32. Determinants of Successful Aging: Findings from a Study with Ergoloid Mesylates (Hydergine).- 33. Differential Patient Response to Ergoloid Mesylates According to Current Etiopathic Notions of Dementia.- 34. A Dose-Response Study of Dihydroergotoxine (DHET) Mesylate for Cerebrovascular Disturbances.- X. Psychiatric Treatment in the Future.- 35. The Mental Health Professional in a Preventive Role.- 36. Concepts of Depression in the Elderly: Signposts to Future Mental Health Needs.- 37. Psychiatric Treatments for the Aged: 2000 and Beyond.- 38. Aging and Mental Retardation: An International Perspective.- 39. Senile Dementia: Psychological and Behavioral Treatments.- 40. Implications of New Research for Care of Alzheimer's Disease.- 41. The Future of Psychotherapy and the Elderly.- XI. A Look into the Future.- 42. "Old Wine in New Bottles": Medical Care for the Elderly in the Year 2000.- 43. Health Care in the 21st Century: The Social and Ethical Context.- 44. Future Diagnostic and Therapeutic Strategies: A Realistic Forecast.- Epilogue.
The seventeenth annual symposium sponsored by the Texas Research Institute of Mental Sciences was held October 23-26, 1983, in Houston, Texas. The theme was Aging 2000: Our Health Care Destiny. This volume on biomedical aspects and a companion volume on psycho social aspects include edited versions of the presentations by about 80 speakers. Their papers were directed at practitioners, researchers, and medical educators who will be active and productive in the year 2000, and we focused on those who would influence the evolution of care of elderly persons during the next 17 years. We chose topics that would be of particular interest to teachers and current planners in the disciplines concerned with delivery of health and social services. We believe that having a core of more qualified and better trained practitioners will help the population of aged persons achieve a higher level of physical and mental health, life satisfaction and happiness, to find better coping techniques and control of environmental stresses, and to attain personal and social goals. Our Goals While preparing for the symposium we knew that the status of the art in 1983 obviously would be the base from which we would work, but we asked our speakers to give priority to future planning and directions.
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