"Lymphocyte Development" presents an extremely up-to-date account of molecular processes involved in the development of lymphocytes. This well written book is based on a graduate course taught by the author. Topics include the selection processes involved in lymphocyte maturation, immune receptor gene rearrangement, signaling pathways involved in cell cycle progression and apoptosis, and the tranillegalscriptional regulation of lymphoid ontogeny. The book also covers T cell development and differentiation of helper and cytotoxic T cells as well as the development of Natural Killer lymphocytes. The book finishes with an account of the molecular basis of immunodeficiency syndromes. It will interest researchers in immunology and it will be useful as a supplementary text for a graduate level immunology course.|"Lymphocyte Development" presents an extremely up-to-date account of molecular processes involved in the development of lymphocytes. This well written book is based on a graduate course taught by the author. Topics include the selection processes involved in lymphocyte maturation, immune receptor gene rearrangement, signaling pathways involved in cell cycle progression and apoptosis, and the tranillegalscriptional regulation of lymphoid ontogeny. The book also covers T cell development and differentiation of helper and cytotoxic T cells as well as the development of Natural Killer lymphocytes. The book finishes with an account of the molecular basis of immunodeficiency syndromes. It will interest researchers in immunology and it will be useful as a supplementary text for a graduate level immunology course.|"Lymphocyte Development" presents an extremely up-to-date account of molecular processes involved in the development of lymphocytes. Topics include the selection processes involved in B and T lymphocyte maturation, immune receptor gene rearrangement, signaling pathways involved in cell cycle progression and apoptosis, and the tranillegalscriptional regulation of lymphoid ontogeny. It will interest researchers in immunology and it will be useful as a supplementary text for a graduate level immunology course.
1 Overview of Cell Fate Decisions During Lymphoid Ontogeny.- 2 Commitment to a Lymphoid Fate.- 3 V(D)J Recombination and the Generation of Diversity.- 4 Pathways Mediating Signal Transduction and Cell Cycle Progression in Lymphocytes.- 5 Molecular Mechanisms of Lymphocyte Apoptosis.- 6 Lymphocyte Homing and the Generation of Secondary Lymphoid Organs.- 7 The Generation of Naive B Lymphocytes.- 8 Antigen-Induced B-Lymphocyte Differentiation.- 9 T Lymphocyte Development.- 10 The Activation and Differentiation of Mature T Lymphocytes.- 11 The Development of Natural Killer Cells.- 12 Naturally Occurring Disorders of Lymphocyte Development.
"Lymphocyte Development" presents an extremely up-to-date account of molecular processes involved in the development of lymphocytes. This well written book is based on a graduate course taught by the author. Topics include the selection processes involved in lymphocyte maturation, immune receptor gene rearrangement, signaling pathways involved in cell cycle progression and apoptosis, and the tranillegalscriptional regulation of lymphoid ontogeny. The book also covers T cell development and differentiation of helper and cytotoxic T cells as well as the development of Natural Killer lymphocytes. The book finishes with an account of the molecular basis of immunodeficiency syndromes. It will interest researchers in immunology and it will be useful as a supplementary text for a graduate level immunology course.
Inhaltsverzeichnis
1 Overview of Cell Fate Decisions During Lymphoid Ontogeny.- 2 Commitment to a Lymphoid Fate.- 3 V(D)J Recombination and the Generation of Diversity.- 4 Pathways Mediating Signal Transduction and Cell Cycle Progression in Lymphocytes.- 5 Molecular Mechanisms of Lymphocyte Apoptosis.- 6 Lymphocyte Homing and the Generation of Secondary Lymphoid Organs.- 7 The Generation of Naive B Lymphocytes.- 8 Antigen-Induced B-Lymphocyte Differentiation.- 9 T Lymphocyte Development.- 10 The Activation and Differentiation of Mature T Lymphocytes.- 11 The Development of Natural Killer Cells.- 12 Naturally Occurring Disorders of Lymphocyte Development.
Klappentext
"Lymphocyte Development" presents an extremely up-to-date account of nmolecular processes involved in the development of lymphocytes. This nwell written book is based on a graduate course taught by the author. nTopics include the selection processes involved in lymphocyte nmaturation, immune receptor gene rearrangement, signaling pathways ninvolved in cell cycle progression and apoptosis, and the ntranillegalscriptional regulation of lymphoid ontogeny. The book also covers nT cell development and differentiation of helper and cytotoxic T cells nas well as the development of Natural Killer lymphocytes. The book nfinishes with an account of the molecular basis of immunodeficiency nsyndromes. It will interest researchers in immunology and it will be nuseful as a supplementary text for a graduate level immunology ncourse.
"Lymphocyte Development" presents an extremely up-to-date account of
molecular processes involved in the development of lymphocytes. Topics
include the selection processes involved in B and T lymphocyte
maturation, immune receptor gene rearrangement, signaling pathways
involved in cell cycle progression and apoptosis, and the
tranillegalscriptional regulation of lymphoid ontogeny. It will interest
researchers in immunology and it will be useful as a supplementary
text for a graduate level immunology course.
