Part I.Etiology and Pathogenesis.Molecular Genetics of Pancreatic Carcinoma,Christopher A. Moskaluk and Scott E. Kern.Role of Polypeptide Growth Factors and Their Receptors in Human Pancreatic Cancer,Murray Korc. Growth Factors and Growth Factor Receptors in Chronic Pancreatitis, and the Relation to Pancreatic Cancer Helmut Friess, Pascal Berberat, and Markus W. Büchler. Clues from Experimental Models, Daniel S. Longnecker. Role for Transforming Growth Factor-b: Clues from Other Cancers, Leslie I. Gold and Trilok Parekh. Part II. Diagnosis and Staging. Screening for Pancreatic Cancer Using Techniques to Detect Altered Gene Products,Robb E. Wilentz, Robbert J. C. Slebos, and Ralph H. Hruban. Tumor Antigens in Pancreatic Cancer, Carlos Rollhauser and William Steinberg. Radiologic Techniques for Diagnosis and Staging of Pancreatic Carcinoma,Mark E. Baker. Diagnosis and Staging of Pancreatic Cancer: The Role of Laparoscopy, Margaret Schwarze and David W. Rattner. Part III.Treatment. Standard Forms of Pancreatic Resection, Peter W. T. Pisters, Jeffrey E. Lee, and Douglas B. Evans. Extended Radical Whipple Resection for Cancer of the Head of the Pancreas: Operative Procedure and Results in Our Institution, F. Hanyu, T. Imaizumi, M. Suzuki, N. Harada, T. Hatori, and A. Fukuda. Extended Pancreatic Resection for Carcinoma of the Pancreas, Tatsushi Naganuma and Yoshifumi Kawarada. Endoscopic Stents for Palliation in Patients with Pancreatic Cancer, Richard C. K. Wong and David L. Carr-Locke. Laparoscopic Biliary and Gastric Bypass, Kevin C. Conlon and Stanley W. Ashley. Chemotherapy of Pancreatic Cancer, Margaret Tempero. Radiation Therapy for Pancreatic Cancer, Tyvin A. Rich. Gene Therapy for Pancreatic Cancer, Nicholas R. Lemoine. Quality of Life in Pancreatic Cancer, D. Fitzsimmons and C. D. Johnson. Index.
A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances.
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