Preface.-Introductory Course.-Dynamic Phenomena in Cells.-Voltage Gated Ionic Currents.-Transporters and Pumps.-Fast and Slow time Scales.-Whole Cell Models.-Intercellular Communication.-Advanced Material.-Spatial Modeling.-Modeling Intracellular Calcium Waves and Sparks.-Biochemical Oscillations.-Cell Cycle Controls.- Modeling the Stochastic Gating of Ion Channels.-Molecular Motors: Theory.-Molecular Motors: Examples.-Numerical Algorithms.-References.-Index.
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.
- Biological examples motivate concepts and techniques used in computational cell biology through a progression of increasingly more complex cellular functions modelled with complex mathematical computational techniques. - A focused introduction that is aimed at advanced undergraduate and graduate biologists and who are mathematically minded and math students who wish to learn about modeling in cell biology.