Nucleotide Exchange Factors for Hsp70 Molecular Chaperones.- Functions of the Hsp90-Binding FKBP Immunophilins.- Hop: An Hsp70/Hsp90 Co-Chaperone that Functions within and beyond Hsp70/Hsp90 Protein Folding Pathways.- Do Hsp40s Act as Chaperones or Co-Chaperones?- The Chaperone and Co-Chaperone Activities of Cdc37 during Protein Kinase Maturation.- UNC-45: A Chaperone for Myosin and a Co-Chaperone for Hsp90.- The Roles of GroES as a Co-Chaperone for GroEL.- Co-Chaperones of the Endoplasmic Reticulum.- The Evolution and Function of Co-Chaperones in Mitochondria.- From Creator to Terminator: Co-Chaperones that Link Molecular Chaperones to the Ubiquitin/Proteasome System.- The Role of Hsp70 and its Co-Chaperones in Protein Misfolding, Aggregation and Disease.- Index.
The Networking of Chaperones by Co-chaperones updates the current understanding of how chaperones are regulated and networked. It is a resource for those in the specialized field of cell stress and chaperones. The book will also be of interest to those in broader cross-cutting field such as cellular networks and systems biology.
Intended as a ready resource for key information on the concepts underpinning the regulation of chaperone by co-chaperones