Introduction * DNA Microarray Technology * Design of DNA Microarray Experiments * Image Analysis * Quality Control * Array Normalization * Class Comparison * Class Prediction * Class Discovery
The analysis of gene expression profile data from DNA micorarray studies are discussed in this book. It provides a review of available methods and presents it in a manner that is intelligible to biologists. It offers an understanding of the design and analysis of experiments utilizing microarrays to benefit scientists. It includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is available from the National Cancer Institute.
Microarray analysis is a very active research area in biology and
statistical genetics. This book presents modern methods at a level
accessible to biologists.