Müller Cells in the Healthy Retina.- Müller Cells in the Diseased Retina.- Conclusions and Perspectives.
Müller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from Müller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Müller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis.
Provides a comprehensive review of Müller glial cells in the retina
Contains color images
Will be of interest to neuroscientists as well as ophthalmologists