Fish oil and importance of its ingredients in human diet.- Transport, synthesis, and incorporation of n-3 and n-6 fatty acids in brain glycerophospholipids.- Release of n-3 and n-6 fatty acids from glycerophospholipids in brain.- Oxidation of arachidonic and docosahexaenoic acids and neurochemical effects of their metabolites on brain.- Roles of DHA and EPA in brain.- Status of docosahexaenoic acid levels in aging and consequences of docosahexaenoic acid deficiency in normal brain.- Status, and therapeutic importance of n-3 fatty acids in neurodegenerative disease.- Status and therapeutic importance of n-3 fatty acids in acute metabolic trauma and neurotraumatic disorders.- Status and therapeutic importance of n-3 fatty acids in neuropsychiatric disorders.- Status and therapeutic importance of n-3 fatty acids in other neural and non-neural diseases.- Perspective and directions for future development on neurochemistry and roles of docosahexaenoic acid.- Index.
It is becoming increasingly evident that the deficiency of n-3 fatty acids in diet is not only associated with cardiovascular diseases, but also involved in stroke, epilepsy and other neurological and neurodegenerative diseases, such as Alzheimer disease, Parkinson disease, and peroxisomal diseases.
In his newest book, Beneficial Effects of Fish Oil on Human Brain, Dr. Akhlaq A. Farooqui expands on the status and therapeutic importance of n-3 fatty acids (major components of fish oil) and their mediators in normal brain and those with neurodegenerative and neuropsychiatric diseases. Farooqui presents the benefits of n-3 fatty acids on Western diet, which is enriched in n-6 fatty acids (major components of vegetable oil) and may promote the above neurological disorders. The book will present readers with cutting edge and comprehensive information on metabolism and roles of neural membrane n-3 fatty acids.
Can be used as supplement text for a range of neuroscience and nutrition courses
Clinicians, neurologists, neuropathologists, ophthalmologists, dietitians, and nutritionists will find this book useful for understanding molecular basis of n-3 fatty acids and their lipid mediators in neuroprotection in acute neural trauma and neurodegenerative diseases