Über den Autor
Edward J. Estlin, BSc (Hons), PhD, MRCP, FRCPCHnMacmillan Consultant in Paediatric Oncology, Department of Paediatric Oncology, Royal Manchester Children's Hospital, Manchester, UKrnRichard J. Gilbertson, B.Med.Sci (Hons), MRCP, PhDnCo-Leader, Neurobiology and Brain Tumor Program; Director, Molecular Clinical Trials Core, Departments of Developmental Neurobiology and Oncology, St Jude Children's Research Hospital, Memphis, TN, USArnRobert F. Wynn, BA, MD, MRCP, FRCPathnConsultant Paediatric Haematologist and Programme Director, Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester, UK
Contributors.rn1 Introduction (Edward J. Estlin, Richard J. Gilbertson and Robert F. Wynn).rnPart I Central Nervous System Tumors of Childhood.rn2 Low- and High-Grade Glioma (Ian F. Pollack).rn3 Ependymoma (Thomas E. Merchant and Richard J. Gilbertson).rn4 Embryonal Tumors (Amar Gajjar and Steven C. Clifford).rn5 Pediatric Spinal Cord Tumors (Annie Huang, Ute Bartels and Eric Bouffet).rn6 Pediatric Craniopharyngioma, Mixed Glioneuronal Tumors, and Atypical Teratoid/Rhabdoid Tumor (Adrienne Weeks and Michael D. Taylor).rnPart II Hematological Disorders.rn7 Acute Lymphoblastic Leukemia (Robert F. Wynn).rn8 Acute Myeloid Leukemia and Myelodysplastic Disorders (David K.H. Webb).rn9 Non-Hodgkin's Lymphoma (Angelo Rosolen and Lara Mussolin).rn10 Hodgkin's Lymphoma (Wolfgang Dörffel and Dieter Körholz).rn11 Histiocytic Disorders (Sheila Weitzman and R. Maarten Egeler).rnPart III Solid Tumors of Childhood.rn12 Neuroblastoma (Sucheta J. Vaidya and Andrew D. J. Pearson).rn13 Renal Tumors (Edward J. Estlin and Norbert Graf).rn14 Soft Tissue Sarcoma (Gianni Bisogno and John Anderson).rn15 Bone Tumors (Richard Gorlick, Martha Perisoglou and Jeremy Whelan).rn16 Hepatic Tumors (Penelope Brock, Derek J. Roebuck and Jack Plaschkes).rn17 Germ Cell Tumors (James Nicholson and Roger Palmer).rn18 Retinoblastoma (Edward J. Estlin, François Doz and Michael Dyer).rn19 Rare Tumors (Bernadette Brennan and Charles Stiller).rnPart IV Supportive Care, Long-Term Issues, and Palliative Care.rn20 Supportive Care: Physical Consequences of Cancer and its Therapies (Bob Phillips and Roderick Skinner).rn21 Psychosocial Needs of Children with Cancer and Their Families (Ged Lalor and Louise Talbot).rn22 Late Effects in Relation to Childhood Cancer (Louise Talbot and Helen Spoudeas).rn23 Palliative Care (Lynda Brook).rn24 Clinical Trials Involving Children with Cancer - Organizational and Ethical Issues (Sue Ablett and Edward J. Estlin).rnIndex.rnColour plate.
This new textbook has an international authorship and is a practical, up-to-date resource for clinicians responsible for the care of children with oncologic and malignant hematologic disease. It is specifically designed for practicing oncologists and hematologists, pediatricians with an interest in childhood cancer and trainees seeking a systematic approach to these disorders. This new textbook has an emphasis on the visual presentation and ease of reading of contemporary and comprehensive information for children's cancers and contains detailed tables, fact boxes and illustrations.rnThe textbook begins with an introduction to the general principles of the scientific foundation and treatment of childhood cancers and hematological malignancies. Separate sections are then devoted to descriptions of central nervous system tumors, hematological malignancies and solid tumors of childhood which encompass epidemiology, cellular and molecular biology, cancer genetics, immunology, pharmacology and the findings of clinical trials. For each area of science covered, key original references and reviews are highlighted to direct further reading.rnDiagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence supporting the current rationales for risk stratification and the development of novel therapies. A final section then explores supportive care, palliative care, late effects considerations and psychosocial issues as relate to children's cancer.