Authentic coverage of fundamental processes in cancer
State-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer
Leading authorship
The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monogaph presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It would be of particular interest to members of the cancer research community, especially those who are actively involved in the study of basic and translational aspects of human cancer. Specifically, this volume includes authentic subject reviews by leading experts on the following aspects:
- Control of tumor cell motility
- Role of tumor-cell adhesion and migration in organ-selective metastasis-formation
- Tumor heterogeneity in relation to invasion and metastasis and its clinical implications
- Tumor angiogenesis, angioprevention, anti-angiogenic therapies and response
- Role of apoptosis in the development, progression and therapy of cancer
- Role of macrophages in tumor development and metastasis
- Pathways of macrophage-mediated tumor progression
- Abnormal variation of immune response against cancer
- Immunological aspects of Marek´s disease virus (MDV)-induced lymphoma progression
- A biodynamical model of human T-cell proliferative disorders
- Current methodologies for characterization of tumor directed immune response
Chapter 1: Metastasis: A Current PerspectiveDavid T. Denhardt, Ann F. Chambers, Danny R. Welch Chapter 2: Control of Cell Motility during Tissue InvasionJames Varani Chapter 3: Cell adhesion and invasion during secondary tumor formationPeter Gassmann, Jörg Haier and Garth L. Nicolson Chapter 4: Genes and MetastasisAlison L. Allan and Ann F. Chambers Chapter 5: The evolution of diversity within tumors and metastasesRakesh K. Singh and James E. Talmadge Chapter 6: Tumor angiogenesis, antiangiogenic therapy and anti-antiangiogenesis responseMengfeng Li Chapter 7: Apoptosis and CancerLászló Kopper, István Peták Chapter 8: Macrophages in Tumour Development and MetastasisAlexandra Eichten, Karin E. de Visser, Lisa M. Coussens Chapter 9: Classical and alternative activation of macrophages: different pathways of macrophage-mediated tumor promotionJo Van Ginderachter, Yuanqing Liu, Nick Devoogdt, Wim Noël, Lea Brys, Gholamreza Hassanzadeh Gh., Geert Raes, Anja Geldhof, Alain Beschin, Hilde Revets and Patrick De Baetselier Chapter 10: Characterization of tumor-directed cellular immune responses in humansDirk Nagorsen, Vladia Monsurro and Francesco M. Marincola Chapter 11: Abnormal variation of the immune response as related to cancerGerhard R.F. Krueger and Maximilian Buja Chapter 12: Immunological Aspects of Marek´s Disease Virus (MDV)-induced Lymphoma ProgressionMark S. Parcells and Shane C. Burgess Chapter 13: A Biodynamical Model of Human T-Cell Development and Pathology: Design, Testing and ValidationMichael E. Brandt, Gerhard R. F. Krueger and Guanyu Wang
The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It would be of particular interest to members of the cancer research community, especially those who are actively involved in the study of basic and translational aspects of human cancer. Specifically, this volume includes authentic subject reviews by leading experts on the following aspects:
- Control of tumor cell motility
- Role of tumor-cell adhesion and migration in organ-selective metastasis-formation
- Tumor heterogeneity in relation to invasion and metastasis and its clinical implications
- Tumor angiogenesis, angioprevention, anti-angiogenic therapies and response
- Role of apoptosis in the development, progression and therapy of cancer
- Role of macrophages in tumor development and metastasis
- Pathways of macrophage-mediated tumor progression
- Abnormal variation of immune response against cancer
- Immunological aspects of Marek's disease virus (MDV)-induced lymphoma progression
- A biodynamical model of human T-cell proliferative disorders
- Current methodologies for characterization of tumor directed immune response.
Metastasis: a current perspective.- Control of cell motility during tissue invasion.- Cell adhesion and invasion during secondary tumor formation: interactions between tumor cells and host organs.- Genes and metastasis: experimental advances and clinical implications.- The evolution of diversity within tumors and metastases.- Tumor angiogenesis, antiangiogenic therapy and anti-antiangiogenesis response.- Apoptosis and cancer.- Macrophages in tumour development and metastasis.- Classical and alternative activation of macrophages: different pathways of macrophage-mediated tumor promotion.- Characterization of tumor-directed cellular immune responses in humans.- Immunological aspects of Marek's disease virus (MDV)-induced lymphoma progression.- Abnormal variation of the immune response as related to cancer.- A biodynamical model of human T-cell development and pathology: design, testing and validation.
Inhaltsverzeichnis
Chapter 1: Metastasis: A Current Perspective
David T. Denhardt, Ann F. Chambers, Danny R. Welch Chapter 2: Control of Cell Motility during Tissue Invasion
James Varani Chapter 3: Cell adhesion and invasion during secondary tumor formation
Peter Gassmann, Jörg Haier and Garth L. Nicolson Chapter 4: Genes and Metastasis
Alison L. Allan and Ann F. Chambers Chapter 5: The evolution of diversity within tumors and metastases
Rakesh K. Singh and James E. Talmadge Chapter 6: Tumor angiogenesis, antiangiogenic therapy and anti-antiangiogenesis response
Mengfeng Li Chapter 7: Apoptosis and Cancer
László Kopper, István Peták Chapter 8: Macrophages in Tumour Development and Metastasis
Alexandra Eichten, Karin E. de Visser, Lisa M. Coussens Chapter 9: Classical and alternative activation of macrophages: different pathways of macrophage-mediated tumor promotion
Jo Van Ginderachter, Yuanqing Liu, Nick Devoogdt, Wim Noël, Lea Brys, Gholamreza Hassanzadeh Gh., Geert Raes, Anja Geldhof, Alain Beschin, Hilde Revets and Patrick De Baetselier Chapter 10: Characterization of tumor-directed cellular immune responses in humans
Dirk Nagorsen, Vladia Monsurro and Francesco M. Marincola Chapter 11: Abnormal variation of the immune response as related to cancer
Gerhard R.F. Krueger and Maximilian Buja Chapter 12: Immunological Aspects of Marek's Disease Virus (MDV)-induced Lymphoma Progression
Mark S. Parcells and Shane C. Burgess Chapter 13: A Biodynamical Model of Human T-Cell Development and Pathology: Design, Testing and Validation
Michael E. Brandt, Gerhard R. F. Krueger and Guanyu Wang
Klappentext
The processes of tumor metastasis, apoptosis and anti-tumor immune response are among the most complex yet rapidly advancing fields in the area of cancer research. This monograph, with its leading authorship, presents a comprehensive coverage of the recent advances in the various key concepts in these fundamental aspects of human cancer. It contains state-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer.
Authentic coverage of fundamental processes in cancer
State-of-the-science reviews on invasion, metastasis, angiogenesis, apoptosis and immunologic aspects related to cancer
Leading authorship
