Plenary Lecture. Recombinant expression of human collagens; J. Myllyharju.
Symposium: Recent Advances in the Materials and Reconstructive Therapy and Tissue Engineering. Expression profiling of parietal endoderm cells and development of systems for large-scale production of laminins; Y. Hayashi, et al. Synthetic peptides from laminin for tissue engineering; M. Mochizuki, M. Nomizu. A novel technology for conversion of in vivo tissue architecture into a three-dimensional in vitro culture mode; T. Takezawa. Construction of liver model with genetically engineered human HepG2 cells; T. Omasa, S. Enosawa.
Structural Biology and Signal Transduction of Animal Cells. Determinants of ligand specificity in groups I and IV WW domains; Y. Kato, et al. Role of the WW domain in signaling and disease; M. Sudol. Structural biology of signal transduction mediated by Grb2; F. Inagaki.
Cell Regulatory Functions of Food Factors and Natural Resources with Special Reference to Health Promotion and Disease Prevention. Modulation of leukocyte function by food factors; M. Yamazaki, H. Ueda. Anticancer effects of lignans; N. Saarinen, et al. Effect of sulfur-containing active principles in garlic on the physiological function of hepatocytes; L.Y. Sheen. Suppression of free radical-induced mutation of animal cell genes by food factors; A. Murakami, et al.
Glycoengineering in Animal Cell Technology. Chemoenzymatic approaches for the preparation of oligosaccharides and glycopeptides; K. Ajisaka.
ESACT Special Lecture: Production of Biologicals. Cell growth arrest by nucleotides as a tool for improved production of biopharmaceuticals; A.V. Carvalhal, et al.
Cell Culture Engineering. Transient gene expression: A novel mammalian cell-based technology for recombinant protein production; F.M. Wurm, et al.
Gene Therapy. Optimization of the production of retroviral vectors: Influences of the sugar source; B. Gény-Fiamma, et al.
Session: Cell Culture Engineering. Effects of glucose and CO 2 concentrations on CHO cell physiology; S. Takuma, et al. Suppression of glutamate-induced neural cell death by electrolyzed-reduced water; T. Kashiwagi, et al. Development of apoptosis-resistant dihydrofolate reductase-deficient Chinese hamster ovary cell line; S.K. Lee, G.M. Lee. High expression of human monoclonal antibodies in CHO cells selected using a cycloheximide resistance marker; M. Tsukahara, et al. Development of a serum-free medium supplemented with hydrolysate for the suspension culture of recombinant CHO cells producing human thrombopoietin; Y.H. Sung, G.M. Lee. Effect of growth factors and ascorbic acid 2-phosphate on liver specific functions of porcine hepatocytes; A. Okamura, et al. Culture of porcine hepatocytes using radial flow bioreactor system; Y. Shiba, et al. The role of glutamine in hybridoma cell culture; H. Matsuoka, et al. 8 Additional Articles.
Production of Biologicals. An engineering method to high yielding production of recombinant anti-HIV monoclonal antibody using generic multi feed fermentation; K. Kawatsu, et al. Proliferation and monoclonal antibody production of hybridoma cells immobilized on non-woven polyester fabric disks; E. Aslankaraoglu, et al. Mass production in yeast of laminins as the material of reconstructive therapy; K. Mizuno, et al.
Functional Cell Lines. Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line A549; A.T. Koparal, M. Zeytinoglu. Establishment of dendritic cell line from caspase-1-deficient mice; B. Nowak, et al. Isolation and characterization of fetal bovine cells derived from liver and bone marrow; T. Takenouchi, T. Takezawa. Artificial selection of high proliferating and apoptosis-resistant NS0 cells for industrial production systems; D. Chau, M. Al-Rubeai.
Immunologicals, Monoclonal Antibodies and Vaccines. Endothelial cells culture and its use to produce a vaccine against rickettsiae; V. Hedrick, et al. Monocytes suppress immune responses of peripheral blood lymph
Animal cell technology is a growing discipline of cell biology which aims not only to understand structures, functions and behaviors of differentiated animal cells, but also to ascertain their abilities to be used in industrial and medical purposes. The goal of animal cell technology includes accomplishments of clonal expansion of differentiated cells with useful ability, optimization of their culture conditions, modulation of their ability for production of medically and pharmaceutically important proteins and the application of animal cells to gene therapy, artificial organs and functional foods.
This volume gives the readers a complete review of present state-of-the-art in Japan and other countries where this field is well advanced. The Proceedings will be useful for the cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and other disciplines related to animal cell culture, working in either academic environments or in industries of biotechnology and pharmacy.