Contributors. Foreword. How Insulin Came From Heidelberg To Aachen and Why It Took five Years; H. Zahn. Insulin at The German Wool Research Institute - Retrospect and Outlook; D. Brandenburg. Insulin: Sequence, Structure and Function - A Story of Surprises; G.G. Dodson, J.L. Whittingham. The Association/Dissociation equilibria of insulin in the presence of metal ions: A Fluorescence Energy Transfer and Circular Dichroism Study; U. Hassiepen, et al. Self-association of Insulin Reconsidered; A. Wollmer, T. Müders. Self-association of Insulin Reconsidered; T. Mülders, A. Wollmer. T-R Transition; A. Wollmer. Comparison of Conformational Transitions in Proteins; P. Krüger. Activities of Insulin Analogues at Position A8 are Uncorrelated with Thermodynamic Stability; M.A. Weiss, et al. Relationships between the Structure of Insulin and its Physiological Effects; R.H. Jones, F. Shojaee-Moradie. Structure-Function Relationships of Insulin and Insulin-Like Growth Factor-I Receptor Binding; P. De Meyts, J. Whittaker. Structural Relationships Between Members of the Insulin Receptor Family; C.W. Ward, et al. Insulin Interaction with Minimized Receptors and Binding Proteins; C. Kristensen, A.S. Andersen. Identification of Susceptibility Loci for Obesity, Insulin Resistance, and Hyperglycemia in a Backcross Model of New Zealand Obese (NZO) and Lean SJL MICE; L. Plum et al. Activation Mechanism of fibroblast growth factor receptor tyrosine kinase revealed by crystal structure of fibroblast growth factor receptor ectodomain bound to fibroblast growth factor and heparin; L. Pellegrini, et al. IL-6 type cytokine receptor complexes; J. Grötzinger. Inhibition of growth factor stimulated pathways for the treatment of prostate cancer; F. Bost, et al. Molecular Dynamics Simulationsof Carbonmonoxy Myoglobin and Calculations of Heme Circular Dichroism; R.W. Woody, et al. Author Index. Keywords.