Preface. nSymposium. Approaches to Human Gene Therapy for Next Century. Application of Chip Technology in Molecular and Cellular Biology. Mesenchymal Stem Cells for Reconstructive Surgery. Advanced Functional Foods and Water for Prevention of Diseases. Molecular Biology of Fish Cells in vitro. Search for Bioactive Substances Using Animal Cells (Satellite Symposium Karatsu). nSession. Cell Culture Engineering. Production of Biologicals. Functional Cell Lines. Glycoengineering. Immunologicals, Monoclonal Antibodies, and Vaccines. Transplantation, Artificial Organs, and Organ Substitutes. Transgenic Animals. Safety and Regulation. Cell Regulatory Factors and Signal Transduction. Functional Substances in Food and Natural Sources. Animal Cells for in vitro Assay. nAuthor Index. Subject Index.
Animal cell technology is a growing discipline of cell biology, which aims not only to understand structures, functions, and behaviours of differentiated animal cells but also to ascertain their ability to be used for industrial and medical purposes. The goal of animal cell technology includes accomplishments of clonal expansion of differentiated cells with useful ability, optimisation of their culture conditions, modulation of their ability for production of medically and pharmaceutically important proteins, and the application of animal cells to gene therapy, artificial organs, and functional foods. This volume gives the reader a complete review of the present state of the art in Japan and other countries where this field is well advanced. The Proceedings will be useful for cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers, and other disciplines related to animal cell culture, working in either academic environments or in industries of biotechnology and pharmacy.