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Formulation & Development of Floating Drug Delivery System
(Englisch)
Formulation, Development and Evaluation of Gastro Retentive Floating Drug Delivery System of Anti-platelet Drug
Pankaj Chasta & Santosh Kumar Gupta & Gaurav Kumar Sharma

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Autor/Autorin: Chasta Pankaj

Pankaj Chasta, a post graduate researcher and Assistant Professor at Department of Pharmacy, Mewar University. I have completed post graduation (M.Pharma ) in Pharmaceutics from Pacific University, Udaipur, Rajasthan, India.
From above experimental findings it can be concluded that: - Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. - The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. - The mechanism of drug release was found to be matrix diffusion controlled. - Formulations showed satisfactory results from Stability studies. - Further in-vivo investigations are necessary to correlate in-vitro data.


Über den Autor

Pankaj Chasta, a post graduate researcher and Assistant Professor at Department of Pharmacy, Mewar University. I have completed post graduation (M.Pharma ) in Pharmaceutics from Pacific University, Udaipur, Rajasthan, India.


Klappentext

From above experimental findings it can be concluded that: ¿ Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. ¿ The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. ¿ The mechanism of drug release was found to be matrix diffusion controlled. ¿ Formulations showed satisfactory results from Stability studies. ¿ Further in-vivo investigations are necessary to correlate in-vitro data.



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