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3-Quinuclidinyl Benzilate
(Englisch)

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3-Quinuclidinyl Benzilate

Produktbeschreibung

High Quality Content by WIKIPEDIA articles! 3- quinuclidinyl benzilate (QNB, BZ, EA-2277), IUPAC name 1-azabicyclo[2.2.2]Oct-3-yl -hydroxy- - phenylbenzeneacetate, is an odorless military incapacitating agent. Its NATO code is BZ. The Iraqi incapacitating agent Agent 15 is believed either to be the same as or similar to BZ. BZ is a glycolate anticholinergic compound related to atropine, scopolamine, hyoscyamine, and other deliriants. Dispersal would be as an aerosolized solid (primarily for inhalation) or as agent dissolved in one or more solvents for ingestion or percutaneous absorption. Acting as a competitive inhibitor of acetylcholine at postsynaptic and postjunctional muscarinic receptor sites in smooth muscle, exocrine glands, autonomic ganglia, and the brain, BZ decreases the effective concentration of acetylcholine seen by receptors at these sites. Thus, BZ causes PNS effects that in general are the opposite of those seen in nerve agent poisoning.