Cushing's Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing's, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility.
Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient's perspective, coping with Cushing's, quality of life, and psychosomatic issues.
This book is essential reading for the wide range of physicians who treat patients with Cushing's disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders.
- Reviews the basics of Cushing's disease and its interrelation with hormones, the brain, and bodily functions
- Includes chapters on diagnosis, surgical, medical, and radiotherapeutic treatments, and variations in presentation, including cyclical disease
- Presents the cognitive and emotional aspects of Cushing's and the long-term sequelae
- Offers an important resource for physicians who are accustomed to treating individual symptoms rather than a disease complex
- Reviews multidisciplinary management, and post-treatment management of Cushing's, including recommendations for Cushing's Centers of Excellence
1. The Pituitary Gland: Anatomy, Physiology, and its Function 2. Epidemiology and Etiology of Cushing's Disease 3. Physical Presentation of Cushing's Syndrome: Typical and Atypical Presentations 4. The Cognitive, Psychological, and Emotional Presentation of Cushing's Disease 5. Making the Diagnosis: Laboratory Testing and Imaging Studies 6. Surgical Treatment of Cushing's Disease 7. Medical Treatment of Cushing's Disease 8. Multidisciplinary Management of Cushing's Disease: Centers of Excellence Approach 9. Posttreatment Management of Cushing's Disease 10. Coping with Cushing's Disease: the Patients' Perspectives 11. Cushing's Disease in Children and Adolescents: Diagnosis and Management 12. Challenges and Future Developments for Improvement in the Diagnosis and Management of Cushing's Disease Appendix. Patients' Perspectives
Edward R. Laws is currently the Director of the Pituitary/Neuroendocrine Center at Brigham and Women's Hospital in Boston and Professor of Surgery at Harvard Medical School. He was formerly the President of the American College of Surgeons and has served as President of the World Federation of Neurosurgical Societies, President of the Congress of Neurological Surgeons, Editor of Neurosurgery, Chairman of the Board of Trustees of the Foundation for International Education in Neurosurgery, Director of the American Board of Neurological Surgery, President of the American Association of Neurological Surgeons, and President of the Pituitary Society.
Founder and President, Cushing's Support and Research Foundation
Klappentext
Cushing's Syndrome outlines the overarching epidemiology of Cushing's as a genetic endocrine disease including valuable statistics on the current incidence and prevalence of the disease. It presents an extensive discussion of the signs and symptoms, including an in-depth discussion of the co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, infections amenorrhea, and infertility. Chapters discuss the surgical treatment of Cushing's, including indications, approaches (e.g., transsphenoidal, craniotomy, adrenalectomy), risks, and complications. Chapters also review the medical treatment, including indications, results, and side effects, and radiotherapy/radiosurgery, including indications, results, risks, and complications. The book also features a chapter offering insight into the patient's perspective, coping with Cushing's, quality of life, and psychosomatic issues. Cushing's Syndrome is essential reading for the wide range of physicians who treat patients with Cushing's Syndrome symptoms, as well as all those biomedical researchers who are investigating the etiology and mechanisms of seemingly rare endocrine disorders, and rare genetic diseases in general.
